Methadone is one of the most popular synthetic opioids in the world with some favorable
properties making it useful both in the treatment of moderate to severe pain and for opioid …

Most agents used for analgesia in small animal patients fall into the opioid or non-steroidal
anti-inflammatory drug groups. The different categories of drugs influence pain processing …

Opioids are the prototypical analgesics, antitussives, and antidiarrheal drug class. The
opioid receptor system or opioid effects have been identified in numerous animal species …

Objective To evaluate the cardiorespiratory, sedative and antinociceptive effects of
dexmedetomidine alone or in combination with methadone, morphine or tramadol in dogs …

Objective To compare the efficacy and side effects of postoperative methadone administered
according to pain score (PS) or every 4 hours (Q4), after unilateral uncomplicated tibial …

The motto of the 2011 Global Year Against Acute Pain was 'Anticipate, Assess, Alleviate'.
Recent advances in acute pain management include novel applications of widely used …

Objective—To determine plasma concentrations and behavioral, antinociceptive, and
physiologic effects of methadone administered via IV and oral transmucosal (OTM) routes in …

Objective To investigate the effects of methadone on the minimum alveolar concentration of
isoflurane (ISO MAC) in dogs. Study design Prospective, randomized cross-over …

OBJECTIVE To evaluate cardiopulmonary, sedative, and antinociceptive effects of
dexmedetomidine combined with commonly administered opioids in dogs. ANIMALS 8 …

Objective To evaluate the cardiopulmonary and sedative effects of xylazine alone or in
combination with methadone, morphine or tramadol in sheep. Study design Experimental …