The progression of cancer involves not only the gradual evolution of cells by mutations in
DNA but also alterations in the gene expression induced by those mutations and input from …

Urological cancers include bladder, prostate and renal cancers that can cause death in
males and females. Patients with urological cancers are mainly diagnosed at an advanced …

For accurate mitotic cell division, replicated chromatin must be assembled into
chromosomes and faithfully segregated into daughter cells. While protein factors like …

The accurate segregation of chromosomes is essential for the survival of organisms and
cells. Mistakes can lead to aneuploidy, tumorigenesis and congenital birth defects. The …

The AurkA serine/threonine kinase is a key regulator of cell division controlling mitotic entry,
centrosome maturation, and chromosome segregation. The microtubule-associated protein …

The process of chromosome congression and alignment is at the core of mitotic fidelity. In
this review, we discuss distinct spatial routes that the chromosomes take to align during …

Cancer cells often display errors in chromosome segregation, some of which result from
improper chromosome alignment at the spindle midplane. Chromosome alignment is …

Lung cancer remains the leading cause of malignant mortality worldwide. Hence, the
discovery of novel targets that can improve therapeutic effects in lung cancer patients is an …

Aneuploidy is a widespread feature of malignant tumors that arises through persistent
chromosome mis‐segregation in mitosis associated with a pathological condition called …

Mitotic kinesin-like protein 2 (MKLP2; also known as KIF20A) is a motor protein with a well-
established function in promoting cytokinesis. However, our results with siRNAs targeting …