CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and
progenitor cells. Clinically, it is associated with the selection and enrichment of …

Background Blood vessel formation is fundamental to development, while its dysregulation
can contribute to serious disease. Expectations are that hundreds of millions of individuals …

Chemical injuries frequently result in vision loss, disfigurement, and challenging ocular
surface complications. Acute interventions are directed at decreasing the extent of the injury …

Conventional allograft therapy for corneal scarring is widespread and successful, but donor
tissue is not universally available, and some grafts fail owing to rejection and complications …

The cornea is our window to the world and our vision is critically dependent on corneal
clarity and integrity. Its epithelium represents one of the most rapidly regenerating …

Purpose: Human limbal palisade of Vogt is an ideal model for studying and practicing
regenerative medicine due to their accessibility. Nonresolving inflammation is a common …

A strong cohort of evidence exists that supports the localisation of corneal stem cells at the
limbus. The distinguishing characteristics of limbal cells as stem cells include slow cycling …

The corneal stroma contains a population of mesenchymal cells subjacent to the limbal
basement membrane with characteristics of adult stem cells. These 'niche cells' support …

The epithelial cell layer that covers the surface of the cornea provides a protective barrier
while maintaining corneal transparency. The rapid and effective turnover of these epithelial …

The limbus is a transition from the cornea to conjunctiva and sclera. In human eyes, this thin
strip has a rich variation of tissue structures and composition, typifying a change from scleral …