Analysis of matrix metalloproteinases, especially MMP‐8, in gingival crevicular fluid, mouthrinse and saliva for monitoring periodontal diseases

T Sorsa, UK Gursoy, S Nwhator… - Periodontology …, 2016 - Wiley Online Library
Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

The ability of quantitative, specific, and sensitive point‐of‐care/chair‐side oral fluid immunotests for aMMP‐8 to detect periodontal and peri‐implant diseases

S Alassiri, P Parnanen, N Rathnayake… - Disease …, 2018 - Wiley Online Library
The analysis of the disease‐specific oral and systemic biomarkers in saliva and oral fluids
(ie, mouth rinse, gingival crevicular fluid (GCF), and peri‐implantitis fluid (PISF)) is …

Active MMP-8 (aMMP-8) as a grading and staging biomarker in the periodontitis classification

T Sorsa, S Alassiri, A Grigoriadis, IT Räisänen… - Diagnostics, 2020 - mdpi.com
The aim of this study was to investigate the utility of incorporating active matrix
metalloproteinase-8 (aMMP-8) as a biomarker into the new periodontitis classification …

Accuracy of single molecular biomarkers in saliva for the diagnosis of periodontitis: A systematic review and meta‐analysis

N Arias‐Bujanda, A Regueira‐Iglesias… - Journal of clinical …, 2020 - Wiley Online Library
Aim To analyse, using a meta‐analytical approach, the diagnostic accuracy of single
molecular biomarkers in saliva for the detection of periodontitis in systemically healthy …

Matrix metalloproteinase‐8 as an inflammatory and prevention biomarker in periodontal and peri‐implant diseases

A Al-Majid, S Alassiri, N Rathnayake… - … journal of dentistry, 2018 - Wiley Online Library
Levels of and especially the degree of activation of matrix metalloproteinase (MMP‐8) in oral
fluids (ie, saliva, mouth rinse, gingival crevicular fluid (GCF) and peri‐implantitis sulcular …

Diagnostic accuracy of oral fluids biomarker profile to determine the current and future status of periodontal and peri-implant diseases

SS Gul, AA Abdulkareem, AM Sha, A Rawlinson - Diagnostics, 2020 - mdpi.com
Severe periodontitis is ranked as the sixth most prevalent disease affecting humankind, with
an estimated 740 million people affected worldwide. The diagnosis of periodontal diseases …

aMMP-8 oral fluid PoC test in relation to oral and systemic diseases

T Sorsa, SO Nwhator, D Sakellari, A Grigoriadis… - Frontiers in oral …, 2022 - frontiersin.org
The manuscript uses the previously published literature and highlights the benefits of active-
matrix metalloproteinase (aMMP)-8 chairside/point-of-care (PoC) diagnostic tools as …

Diagnostic accuracy of a point‐of‐care aMMP‐8 test in the discrimination of periodontal health and disease

K Deng, G Pelekos, L Jin… - Journal of Clinical …, 2021 - Wiley Online Library
Aim To assess the diagnostic utility of an oral rinse active matrix metalloproteinase‐8 (aMMP‐
8) point‐of‐care test (POCT) for differentiating periodontal health, gingivitis, as well as …

Salivary Diagnostics—Point-of-Care diagnostics of MMP-8 in dentistry and medicine

N Rathnayake, DR Gieselmann, AM Heikkinen… - Diagnostics, 2017 - mdpi.com
Human saliva is an easily accessible biological fluid and contains a variety of disease-
related biomarkers, which makes it a potential diagnostic medium. The clinical use of …

Matrix metalloproteinase‐8 levels in periodontal disease patients: A systematic review

EF De Morais, JC Pinheiro, RB Leite… - Journal of …, 2018 - Wiley Online Library
Periodontal disease is characterized as a disorder of the oral microbiota resulting in an
immune response which, in turn, leads to the destruction of periodontal tissue. Matrix …