KIT D816V mast cells derived from induced pluripotent stem cells recapitulate systemic mastocytosis transcriptional profile

MAS de Toledo, X Fu, T Maié, EM Buhl, K Götz… - International Journal of …, 2023 - mdpi.com
Mast cells (MCs) represent a population of hematopoietic cells with a key role in innate and
adaptive immunity and are well known for their detrimental role in allergic responses. Yet …

The impact of the JAK2 V617F mutation on megakaryocytes and bone marrow fibrosis in an iPS cell model

N Flosdorf, R Schneider-Kramann, M Zenke… - 2023 - publications.rwth-aachen.de
Die Erfindung der induzierten pluripotenten Stammzellen (iPS-Zellen) ermöglichte es
Forschern, menschliche Stammzellen, ihre Differenzierung, die Entwicklung von Organen …