Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are a 48-member
superfamily of membrane proteins that actively transport a variety of biological substrates …

Background Addison's disease (AD) is a rare disorder and among adult population in
developed countries is most commonly caused by autoimmunity. In contrast, in children …

Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology.
Besides the canonical regulatory activity on bone metabolism, several non-classical actions …

The adrenal cortex undergoes multiple structural and functional rearrangements to satisfy
the systemic needs for steroids during fetal life, postnatal development, and adulthood. A …

Conditions of impaired adrenal function and tissue destruction, such as in Addison's
disease, and treatment resistance of adrenocortical carcinoma (ACC) necessitate improved …

Adjuvants, as the name indicates, are adjoined material aimed to assist in functioning as
when added to vaccines they are meant to boost the effect and strongly stimulate the …

Context Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is
an autoimmune endocrinopathy with severe and unpredictable course. The impact of …

Transient receptor potential (TRP) channels are polymodal channels capable of sensing
environmental stimuli, which are widely expressed on the plasma membrane of cells and …

Skin pigmentation can occur due to increased melanin, including melanocyte proliferation,
melanin biosynthesis, or melanocyte migration. There are many factors that influence the …

Results Endocrine disorders trigger the onset of menstrual disturbance across the
reproductive lifespan of women. Endocrine glands (pituitary, thyroid, pancreas, adrenal, and …