Psoriatic arthritis from a mechanistic perspective

G Schett, P Rahman, C Ritchlin, IB McInnes… - Nature Reviews …, 2022 - nature.com
Psoriatic arthritis (PsA) is part of a group of closely related clinical phenotypes ('psoriatic
disease') that is defined by shared molecular pathogenesis resulting in excessive …

Psoriatic arthritis: pathogenesis and targeted therapies

AB Azuaga, J Ramírez, JD Cañete - International journal of molecular …, 2023 - mdpi.com
Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease
characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and …

Rheumatic manifestations of chikungunya: emerging concepts and interventions

A Suhrbier - Nature Reviews Rheumatology, 2019 - nature.com
The largest epidemic ever recorded for chikungunya, a disease caused by infection with the
chikungunya virus (CHIKV), began in Africa in 2004 and spread to> 100 countries on four …

Oral dysbiosis and autoimmunity: from local periodontal responses to an imbalanced systemic immunity. A review

LJ Suárez, H Garzón, S Arboleda… - Frontiers in …, 2020 - frontiersin.org
The current paradigm of onset and progression of periodontitis includes oral dysbiosis
directed by inflammophilic bacteria, leading to altered resolution of inflammation and lack of …

Polyfunctional, proinflammatory, Tissue‐Resident memory phenotype and function of synovial Interleukin‐17A+ CD 8+ T cells in psoriatic arthritis

KJA Steel, U Srenathan, M Ridley… - Arthritis & …, 2020 - Wiley Online Library
Objective Genetic associations imply a role for CD 8+ T cells and the interleukin‐23 (IL‐
23)/IL‐17 axis in psoriatic arthritis (PsA) and other spondyloarthritides (SpA). IL‐17A+ CD …

Psoriatic and rheumatoid arthritis joints differ in the composition of CD8+ tissue-resident memory T cell subsets

GAM Povoleri, LE Durham, EH Gray, S Lalnunhlimi… - Cell Reports, 2023 - cell.com
Summary CD69+ CD103+ tissue-resident memory T (T RM) cells are important drivers of
inflammation. To decipher their role in inflammatory arthritis, we apply single-cell, high …

The IL-17/IL-23 axis and its genetic contribution to psoriatic arthritis

M Vecellio, VX Hake, C Davidson, MC Carena… - Frontiers in …, 2021 - frontiersin.org
Psoriatic arthritis (PsA) is a chronic inflammatory disease belonging to the family of
spondyloarthropathies (SpA). PsA commonly aggravates psoriasis of the skin and frequently …

Biomarkers in psoriatic arthritis: A meta-analysis and systematic review

T Wirth, N Balandraud, L Boyer, P Lafforgue… - Frontiers in …, 2022 - frontiersin.org
Introduction Psoriatic arthritis (PsA) is a chronic inflammatory disease that frequently
develops in patients with psoriasis (PsO) but can also occur spontaneously. As a result, PsA …

Therapeutic effects of mesenchymal/stromal stem cells and their derived extracellular vesicles in rheumatoid arthritis

D Tsiapalis, A Floudas, T Tertel… - Stem Cells …, 2023 - academic.oup.com
Currently available therapies for rheumatoid arthritis (RA) are inadequate to alleviate the
inflammation and reduce joint damage. While the immune-regulatory effect of human …

Distinct stromal and immune cell interactions shape the pathogenesis of rheumatoid and psoriatic arthritis

A Floudas, CM Smith, O Tynan, N Neto… - Annals of the …, 2022 - ard.bmj.com
Objectives Immune and stromal cell communication is central in the pathogenesis of
rheumatoid arthritis (RA) and psoriatic arthritis (PsA), however, the nature of these …