Neutrophil chemoattractant receptors in health and disease: double-edged swords

M Metzemaekers, M Gouwy, P Proost - Cellular & molecular …, 2020 - nature.com
Neutrophils are frontline cells of the innate immune system. These effector leukocytes are
equipped with intriguing antimicrobial machinery and consequently display high cytotoxic …

Tumor-associated neutrophils in colorectal cancer development, progression and immunotherapy

W Zheng, J Wu, Y Peng, J Sun, P Cheng, Q Huang - Cancers, 2022 - mdpi.com
Simple Summary Tumor-associated neutrophils (TANs) may differentiate into different
patterns under the stimulation of different factors, and they play a dual role in the occurrence …

Neutrophil-induced liver injury and interactions between neutrophils and liver sinusoidal endothelial cells

Y Wang, Y Liu - Inflammation, 2021 - Springer
Neutrophils are the most abundant type of leukocytes with diverse functions in immune
defense including production of reactive oxygen species, bacteriocidal proteins, neutrophil …

NETosis in ischemic/reperfusion injuries: An organ-based review

P Hashemi, M Nouri-Vaskeh, L Alizadeh… - Life Sciences, 2022 - Elsevier
Neutrophil extracellular trap (NETosis), the web-like structures induced by neutrophil death,
is an important inflammatory mechanism of the immune system leading to reactive oxygen …

Neutrophils: Musketeers against immunotherapy

KR Zahid, U Raza, S Tumbath, L Jiang, W Xu… - Frontiers in …, 2022 - frontiersin.org
Neutrophils, the most copious leukocytes in human blood, play a critical role in
tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have …

Assessing the role of T cells in response to retinal injury to uncover new therapeutic targets for the treatment of retinal degeneration

FM Conedera, JM Runnels, JV Stein, C Alt… - Journal of …, 2023 - Springer
Background Retinal degeneration is a disease affecting the eye, which is an immune-
privileged site because of its anatomical and physiological properties. Alterations in retinal …

Distinguishing sepsis from infection by neutrophil dysfunction: a promising role of CXCR2 surface level

C Seree-Aphinan, P Vichitkunakorn… - Frontiers in …, 2020 - frontiersin.org
Sepsis is one of the well-established diseases with specific patterns of neutrophil
dysfunctions. Previous studies demonstrated sepsis-related neutrophil dysfunctions in …

The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and axonal …

K Yagura, H Ohtaki, T Tsumuraya, A Sato… - PLoS …, 2020 - journals.plos.org
Human bone marrow-derived mesenchymal stem/stromal cells (hMSCs) have shown
potential in facilitating recovery from spinal cord injury (SCI) through communicating with …

Testosterone affects type I/type II interferon response of neutrophils during hepatic amebiasis

M Er-Lukowiak, S Hänzelmann, M Rothe… - Frontiers in …, 2023 - frontiersin.org
Differences in immune response between men and women may influence the outcome of
infectious diseases. Intestinal infection with Entamoeba histolytica leads to hepatic …

Protective effect of pinocembrin from Penthorum chinense Pursh on hepatic ischemia reperfusion injury via regulating HMGB1/TLR4 signal pathway

T Ma, H Zhang, T Li, J Bai, Z Wu, T Cai… - Phytotherapy …, 2023 - Wiley Online Library
Hepatic ischemia–reperfusion injury (HIRI) is of common occurrence during liver surgery
and transplantation. Pinocembrin (PIN) is a kind of flavonoid monomer extracted from the …