Objective: To frame revised guidelines on diagnosis, evaluation, management, and
supportive care of patients with the illness. Process: The guidelines combine evidence …

Justification The emerging literature on prevalence of vitamin D deficiency in India,
prevention and treatment strategies of rickets, and extra-skeletal benefits of vitamin D …

Immunosuppressants are commonly used as steroid-sparing agents in childhood idiopathic
nephrotic syndrome (NS) to induce and sustain remissions. These drugs have narrow …

Background Sequential rituximab (RTX) administration has emerged as an important
strategy to sustain remission of disease in patients with difficult-to-treat nephrotic syndrome …

Nephrotic syndrome is one of the most common chronic kidney diseases (CKD) in children
with an estimated incidence of 2.92 (range 1.15–16.9) per 100,000 children per year [1]. The …

Background Limited data exists regarding the clinical course and outcomes of children with
primary focal segmental glomerulosclerosis (FSGS) from low-and middle-income countries …

Background In pediatric steroid-resistant nephrotic syndrome (SRNS), calcineurin inhibitors
(CNIs) are recommended as first-line therapy, with efficacy ranging between 60 and 80 …

Background and Objective: Tacrolimus, a calcineurin inhibitor widely used as a potent
immunosuppressant to prevent graft rejection, exhibits nonlinear kinetics in patients with …

The management of focal segmental glomerulosclerosis (FSGS) is challenging, and a
definitive long-term cure remains elusive. It is associated with poor outcomes due to …

Background Idiopathic nephrotic syndrome (NS) in children poses treatment challenges,
with a subset developing steroid-resistant nephrotic syndrome (SRNS). Genetic factors play …