Bioinformatic Analysis of Topoisomerase IIα Reveals Interdomain Interdependencies and Critical C-Terminal Domain Residues
CE Endsley, KA Moore, TD Townsley… - International Journal of …, 2024 - mdpi.com
DNA Topoisomerase IIα (Top2A) is a nuclear enzyme that is a cancer drug target, and there
is interest in identifying novel sites on the enzyme to inhibit cancer cells more selectively and …
is interest in identifying novel sites on the enzyme to inhibit cancer cells more selectively and …