Chiral separation and molecular simulation study of six antihistamine agents on a coated cellulose tri‐(3, 5‐dimethylphenycarbamate) column (Chiralcel OD‐RH) and …
Y Liu, X Wang, J Yu, X Guo - Electrophoresis, 2021 - Wiley Online Library
Enantiomeric separation of six antihistamine agents was first systematically investigated on
a cellulose‐based chiral stationary phase (CSP), that is, cellulose tris‐(3, 5‐dimethyl phenyl …
a cellulose‐based chiral stationary phase (CSP), that is, cellulose tris‐(3, 5‐dimethyl phenyl …
Immobilization of chondroitin sulfate a onto monolithic epoxy silica column as a new chiral stationary phase for high-performance liquid chromatographic …
Chondroitin sulfate A was covalently immobilized onto a monolithic silica epoxy column
involving a Schiff base formation in the presence of ethylenediamine as a spacer and …
involving a Schiff base formation in the presence of ethylenediamine as a spacer and …
Retention mechanisms of dipeptides on superficially porous particle vancomycin-and teicoplanin-based chiral stationary phases
EN Reshetova, AS Barashkova, BF Garifullin - Journal of Chromatography …, 2024 - Elsevier
Chromatographic behavior of new chiral stationary phases (CSPs) Chiral-T and Chiral-V
with teicoplanin and vancomycin antibiotics grafted onto superficially porous silica particles …
with teicoplanin and vancomycin antibiotics grafted onto superficially porous silica particles …
Green fluorescence-based approaches for quantitative estimation of the antihistaminic drug meclizine; application to spiked human plasma
Meclizine hydrochloride (MCZ) is a sedating antihistamine having anti-muscarinic
properties. It is mainly recognized for its antiemetic properties. Two eco-friendly, facile, and …
properties. It is mainly recognized for its antiemetic properties. Two eco-friendly, facile, and …
Enantioselective Separation and Pharmacokinetics of a Chiral 1, 4‐Dihydropyrimidine Derivative in Rats: A Combined Chromatography and Docking Approach
ABSTRACT Chirality in 1, 4‐Dihydropyrimidines influences their pharmacological properties
and synthetic strategies. Enantiomers of chiral drugs often exhibit different pharmacokinetic …
and synthetic strategies. Enantiomers of chiral drugs often exhibit different pharmacokinetic …
QSAR Analysis and Molecular Docking Studies of Aryl Sulfonamide Derivatives as Mcl-1 Inhibitors and the Influence of Structure and Chirality on the Inhibitory Activity
J Chen, Y Ma, JW Zou, S Hu… - Letters in Drug Design …, 2024 - benthamdirect.com
Background Mcl-1 is a kind of antiapoptotic protein and its overexpression is closely related
to the occurrence of cancer. Aryl sulfonamide derivatives are expected to become new …
to the occurrence of cancer. Aryl sulfonamide derivatives are expected to become new …
[HTML][HTML] Development and application of an enantioselective liquid chromatography–tandem mass spectrometry method for the quantification of enantiomers to …
SA Shah, M Jairaj, L King - Journal of Chromatography Open, 2023 - Elsevier
To assess whether a suspected metabolic chiral inversion of a new chemical entity (NCE)
with a single chiral centre occurred in an in vivo pharmacokinetic (PK) study of UCB-1, a …
with a single chiral centre occurred in an in vivo pharmacokinetic (PK) study of UCB-1, a …