Contemporary insights and prospects on ferroptosis in rheumatoid arthritis management

H Zhao, Q Dong, H Hua, H Wu, L Ao - Frontiers in Immunology, 2024 - frontiersin.org
Rheumatoid arthritis (RA) is a common autoimmune disease characterized primarily by
persistent synovial inflammation and joint destruction. In recent years, ferroptosis, as a novel …

[HTML][HTML] Role of Oxidative Stress in Blood–Brain Barrier Disruption and Neurodegenerative Diseases

S Kim, UJ Jung, SR Kim - Antioxidants, 2024 - pmc.ncbi.nlm.nih.gov
Upregulation of reactive oxygen species (ROS) levels is a principal feature observed in the
brains of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's …

[HTML][HTML] Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration

AK Ückert, S Rütschlin, S Gutbier, NC Wörz… - Environment …, 2023 - Elsevier
The causes of nigrostriatal cell death in idiopathic Parkinson's disease are unknown, but
exposure to toxic chemicals may play some role. We followed up here on suggestions that …

[HTML][HTML] Iron toxicity, ferroptosis and microbiota in Parkinson's disease: Implications for novel targets

FV Carvalho, HE Landis, B Getachew… - Advances in …, 2024 - ncbi.nlm.nih.gov
Parkinson's Disease (PD) is a progressive neurodegenerative disease characterized by loss
of dopaminergic neurons in substantia nigra pars compacta (SNpc). Iron (Fe)-dependent …

The role of iron overload in diabetic cognitive impairment: A review

JR An, QF Wang, GY Sun, JN Su, JT Liu… - Diabetes, Metabolic …, 2023 - Taylor & Francis
It is well documented that diabetes mellitus (DM) is strongly associated with cognitive
decline and structural damage to the brain. Cognitive deficits appear early in DM and …

The Role of Reactive Oxygen Species in Alzheimer's Disease: from Mechanism to Biomaterials Therapy

Z Yu, F Luo - Advanced Healthcare Materials, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a chronic, insidious, and progressive neuro‐degenerative
disease that remains a clinical challenge for society. The fully approved drug lecanemab …

Cerebral iron accumulation in multiple sclerosis: Pathophysiology and therapeutic implications

G Bjørklund, DR Wallace, T Hangan, M Butnariu… - Autoimmunity …, 2025 - Elsevier
Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system
characterized by demyelination, neuroinflammation, and neurodegeneration. Recent studies …

Ageing-related changes in the regulation of microglia and their interaction with neurons

R von Bernhardi, J Eugenín - Neuropharmacology, 2024 - Elsevier
Ageing is one of the most important risk factors for chronic health conditions, including
neurodegenerative diseases. Inflammation is a feature of ageing, as well as a key …

Silver nanoparticles induce iron accumulation-associated cognitive impairment via modulating neuronal ferroptosis

X Zhai, W Yan, S Liu, L Tian, Y Zhang, Y Zhao… - Environmental …, 2024 - Elsevier
Silver nanoparticles (AgNPs) are widely used in daily life and medical fields owing to their
unique physicochemical properties. Daily exposure to AgNPs has become a great concern …

Benefits of Puerarin on Metabolic Syndrome and Its Associated Cardiovascular Diseases in Rats Fed a High-Fat/High-Sucrose Diet

Y Mu, Y Yang, S Jiang, C Liu, Y Han, J Jiang, Y Wang - Nutrients, 2024 - mdpi.com
Metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular diseases (CVDs)
that has become a global public health problem. Puerarin (PUE), the principal active …