Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

DI Watkins, DR Burton, EG Kallas, JP Moore… - Nature medicine, 2008 - nature.com
Abstract The adenovirus type 5 (Ad5)-based vaccine developed by Merck failed to either
prevent HIV-1 infection or suppress viral load in subsequently infected subjects in the STEP …

Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms

HL Wilson, ACC Wong, SR Shaw, WY Tse… - Journal of medical …, 2003 - jmg.bmj.com
Methods: The 22q13 deletion syndrome (MIM 606232) is characterised by moderate to
profound mental retardation, delay/absence of expressive speech, hypotonia, normal to …

HLA‐DQB1 and‐DQA1 typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours

O Olerup, A Aldener, A Fogdell - Tissue antigens, 1993 - Wiley Online Library
In the present study PCR primers were designed for detecting all phenotypically expressed
DQB1 and DQA1 allelic variability, 19 and 10 alleles, respectively, by PCR amplification with …

Radiological outcome in rheumatoid arthritis is predicted by presence of antibodies against cyclic citrullinated peptide before and at disease onset, and by IgA-RF at …

E Berglin, T Johansson, U Sundin, E Jidell… - Annals of the …, 2006 - ard.bmj.com
Objective: To evaluate the significance of antibodies against cyclic citrullinated peptide (anti-
CCP) and rheumatoid factors (RFs), before the onset of rheumatoid arthritis and when …

Large Scale Identification of Genes Involved in Cell Surface Biosynthesis and Architecture in Saccharomyces cerevisiae

M Lussier, AM White, J Sheraton, T di Paolo… - Genetics, 1997 - academic.oup.com
The sequenced yeast genome offers a unique resource for the analysis of eukaryotic cell
function and enables genome-wide screens for genes involved in cellular processes. We …

Bioelectricity production from blueberry waste

S Rojas-Flores, SM Benites, M De La Cruz-Noriega… - Processes, 2021 - mdpi.com
Global warming and the increase in organic waste from agro-industries create a major
problem for the environment. In this sense, microbial fuel cells (MFC) have great potential for …

Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae.

N Burns, B Grimwade, PB Ross-Macdonald… - Genes & …, 1994 - genesdev.cshlp.org
We have developed a large-scale screen to identify genes expressed at different times
during the life cycle of Saccharomyces cerevisiae and to determine the subcellular locations …

Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection

KS MacDonald, KR Fowke, J Kimani… - The Journal of …, 2000 - academic.oup.com
Certain human leukocyte antigens, by presenting conserved immunogenic epitopes for T
cell recognition, may, in part, account for the observed differences in human …

Salinity stress-tolerant and -sensitive rice (Oryza sativa L.) regulate AKT1-type potassium channel transcripts differently

D Golldack, F Quigley, CB Michalowski… - Plant molecular …, 2003 - Springer
In the indica rice (Oryza sativa L.) a cDNA was characterized that encoded OsAKT1
homologous to inward-rectifying potassium channels of the AKT/KAT subfamily. Transcript …

[图书][B] Pulsed field gel electrophoresis: a practical guide

B Birren, E Lai - 2012 - books.google.com
Pulsed Field Gel Electrophoresis: A Practical Guide is the first laboratory manual to describe
the theory and practice of this technique. Based on the authors' experience developing …