The cGAS-STING pathway in ischemia-reperfusion injury in acute cerebral infarction: a new therapeutic opportunities?

J Hu, M Tian - Frontiers in Neurology, 2024 - frontiersin.org
The innate immune response is the body's first line of defense against external pathogens
and endogenous damage signals. The cGAS-STING pathway is a crucial component of the …

[HTML][HTML] Transcriptome-based characterization of 3'2'-cGAMP signaling mediated immune responses

Y Gao, G Xu, M Maimaiti, S Chen, X Zhang, J Hu… - Computational and …, 2024 - Elsevier
Cyclic dinucleotides (CDNs) are critical adjuvants in antiviral vaccines and cancer
immunotherapy, primarily through the activation of the cGAS-STING signaling pathway …

Suppression of cGAS/STING pathway-triggered necroptosis in the hippocampus relates H2S to attenuate cognitive dysfunction of Parkinson's disease

XL Huang, Y Hu, W Jiang, JM Jiang, W Zou… - Experimental …, 2025 - Elsevier
Background Cognitive dysfunction is the most severe non-motor symptom of Parkinson's
disease (PD). Our previous study revealed that hydrogen sulfide (H 2 S) ameliorates …