The therapeutic effect of highly malignant triple negative breast cancer (TNBC) is negatively
affected by the formation of tumor cell resistant clone and the severe toxicity of …

Small interfering RNA (siRNA) is a relatively novel nucleic acid-based therapy to treat
diseases such as cancer. Nevertheless, substantial obstacles to its clinical applications have …

Polymeric micelles are extensively used for the delivery of hydrophobic drugs, which,
however, suffer from unsatisfactory drug loading, colloidal uniformity, formulation stability …

Human serum albumin nanoparticles (HSA-NPs) are widely-used drug delivery systems with
applications in various diseases, like cancer. For intravenous administration of HSA-NPs …

Combination chemotherapy produces a superior therapeutic response than monotherapy in
cancer. Human serum albumin and a naturally occurring cancer prophylactic/anticancer …

A pathology-adaptive nanosystem, in which nest-like hosts are built based on nanofibers
that are transformed from iv injected nanoparticles under the acidic tumor microenvironment …

Designing a transformable nanosystem with improved tumor accumulation and penetration
by tuning multiple physicochemical properties remains a challenge. Here, a near-infrared …

Combination therapy is one of the important treatment strategies for cancer at present.
However, the outcome of current combination therapy based on the co-administration of …

Triple-negative breast cancer (TNBC) is a destructive disease with a poor prognosis, low
survival rate and high rate of metastasis. It comprises 15% of total breast cancers and is …

Accumulating evidences have suggested the existence of breast cancer stem cells (BCSCs),
which possess the potential of both self-renewal and differentiation. The origin of BCSCs …