RNA-mediated immunotherapy regulating tumor immune microenvironment: next wave of cancer therapeutics

PR Pandey, KH Young, D Kumar, N Jain - Molecular cancer, 2022 - Springer
Accumulating research suggests that the tumor immune microenvironment (TIME) plays an
essential role in regulation of tumor growth and metastasis. The cellular and molecular …

Long non-coding RNAs in the tumor immune microenvironment: biological properties and therapeutic potential

YN Pi, WC Qi, BR Xia, G Lou, WL Jin - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy (CIT) is considered a revolutionary advance in the fight against
cancer. The complexity of the immune microenvironment determines the success or failure …

LncRNA SNHG1 regulates the differentiation of Treg cells and affects the immune escape of breast cancer via regulating miR-448/IDO

X Pei, X Wang, H Li - International journal of biological macromolecules, 2018 - Elsevier
Objective To investigate the mechanism of lncRNA SNHG1 in the immune escape of breast
cancer (BC). Methods SNHG1, miR-448 and IL-10 levels were evaluated by qRT-PCR. The …

The research progress of LncRNA involved in the regulation of inflammatory diseases

K Liao, J Xu, W Yang, X You, Q Zhong, X Wang - Molecular immunology, 2018 - Elsevier
Long non-coding RNA (lncRNA) is a non-coding RNA which lacks a complete open reading
frame (ORF) and plays an important role in biological processes such as cell proliferation …

LncRNAs and immunity: coding the immune system with noncoding oligonucleotides

M Bocchetti, M Scrima, F Melisi, A Luce… - International journal of …, 2021 - mdpi.com
Long noncoding RNAs (lncRNAs) represent key regulators of gene transcription during the
inflammatory response. Recent findings showed lncRNAs to be dysregulated in human …

Noncoding RNAs in the COVID-19 saga: an untold story

M Maqbool, MS Hussain, NK Shaikh, A Sultana… - Viral …, 2024 - liebertpub.com
In late 2019, the SARS-CoV-2 virus emerged as the cause of COVID-19, triggering a
worldwide pandemic of unprecedented scale. A detailed comprehension is being …

[HTML][HTML] SNHG1 promotes cell proliferation by acting as a sponge of miR-145 in colorectal cancer

T Tian, R Qiu, X Qiu - Oncotarget, 2018 - ncbi.nlm.nih.gov
Abstract ncRNAs are important regulatory molecules and involve in many physiological
cellular processes. Small nucleolar RNA host gene 1 (SNHG1) is a host to 8 snoRNAs and …

Plasmodium manipulates the expression of host long non-coding RNA during red blood cell intracellular infection

G Chen, S Liu, X Fan, Y Jin, X Li, Y Du - Parasites & Vectors, 2022 - Springer
Background Parasites interact with their host through “direct” and/or “indirect” mechanisms.
Plasmodium, for example, either mediates direct physical interactions with host factors or …

Panoramic on epigenetics in coronary artery disease and the approach of personalized medicine

M Bergonzini, F Loreni, A Lio, M Russo, G Saitto… - Biomedicines, 2023 - mdpi.com
Epigenetic modifications play a fundamental role in the progression of coronary artery
disease (CAD). This panoramic review aims to provide an overview of the current …

Screening and identification of lncRNAs as potential biomarkers for pulmonary tuberculosis

Z Chen, LL Wei, LY Shi, M Li, TT Jiang, J Chen… - Scientific reports, 2017 - nature.com
Pulmonary tuberculosis (TB) is among the diseases with the highest morbidity and mortality
worldwide. Effective diagnostic methods for TB are lacking. In this study, we investigated …