Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - Elsevier
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

The oxytocin–vasopressin pathway in the context of love and fear

CS Carter - Frontiers in endocrinology, 2017 - frontiersin.org
Vasopressin (VP) and oxytocin (OT) are distinct molecules; these peptides and their
receptors [OT receptor (OTR) and V1a receptor (V1aR)] also are evolved components of an …

Behavioral and epigenetic consequences of oxytocin treatment at birth

WM Kenkel, AM Perkeybile, JR Yee… - Science …, 2019 - science.org
Oxytocin is used in approximately half of all births in the United States during labor induction
and/or augmentation. However, the effects of maternal oxytocin administration on offspring …

Oxytocin and excitation/inhibition balance in social recognition

OL Lopatina, YK Komleva, YV Gorina… - Neuropeptides, 2018 - Elsevier
Social recognition is the sensitive domains of complex behavior critical for identification,
interpretation and storage of socially meaningful information. Social recognition develops …

Role of oxytocin and vasopressin in neuropsychiatric disorders: therapeutic potential of agonists and antagonists

V Cid-Jofré, M Moreno, M Reyes-Parada… - International Journal of …, 2021 - mdpi.com
Oxytocin (OT) and vasopressin (AVP) are hypothalamic neuropeptides classically
associated with their regulatory role in reproduction, water homeostasis, and social …

[HTML][HTML] Multi-level effects driving cognitive and behavioral variability among prairie voles: insights into reproductive decision-making from biological levels of …

SA Forero, AG Ophir - Brain Behavior and Evolution, 2022 - karger.com
Behavioral phenotypes play an active role in maximizing fitness and shaping the
evolutionary trajectory of species by offsetting the ecological and social environmental …

Effects of oxytocin receptor agonism on acquisition and expression of pair bonding in male prairie voles

MC Johnson, JA Zweig, Y Zhang, L Nunez… - Translational …, 2024 - nature.com
There is much interest in targeting the activity in the oxytocin system to regulate social
bonding. However, studies with exogenous administration of oxytocin face the caveats of its …

Individual differences in social behavior and cortical vasopressin receptor: genetics, epigenetics, and evolution

SM Phelps, M Okhovat, A Berrio - Frontiers in Neuroscience, 2017 - frontiersin.org
Social behavior is among the most complex and variable of traits. Despite its diversity, we
know little about how genetic and developmental factors interact to shape natural variation …

DNA methylation and demethylation underlie the sex difference in estrogen receptor alpha in the arcuate nucleus

LR Cortes, CD Cisternas, INKV Cabahug… - …, 2022 - karger.com
Introduction: Neurons expressing estrogen receptor (ER) ɑ in the arcuate (ARC) and
ventromedial (VMH) nuclei of the hypothalamus sex-specifically control energy homeostasis …

Promoter methylation changes and vascular dysfunction in pre-eclamptic umbilical vein

Q Gao, X Fan, T Xu, H Li, Y He, Y Yang, J Chen… - Clinical …, 2019 - Springer
Background Hypertension is one of primary clinical presentations of pre-eclampsia. The
occurrence and progress of hypertension are closely related to vascular dysfunction …