Papers and patents that deal with polymorphism (crystal systems for which a substance can
exist in structures defined by different unit cells and where each of the forms has the same …

Encapsulating a drug molecule into a water‐reactive metal–organic framework (MOF) leads
to amorphous drug confined within the nanoscale pores. Rapid release of drug occurs upon …

In 2010 we energy-minimized 225 high-quality single-crystal (SX) structures with dispersion-
corrected density functional theory (DFT-D) to establish a quantitative benchmark. For the …

Cocrystals of carbamazepine with nicotinamide and saccharin are shown to be polymorphic.
Two polymorphs of carbamazepine− nicotinamide (CBZ-NCT) cocrystals and two …

X-ray powder diffraction is a vital analytical tool that is used in pharmaceutical science. It is
increasingly used to establish the crystal structure of a new pharmaceutical substance, in …

In this study, the capability of the PHSC model was evaluated to predict the solubility of the
pharmaceuticals in pure, mixed, and supercritical solvents over a wide range of …

Rheumatoid arthritis (RA) is a chronic autoimmune joint disorder that affects about 1% of the
world population and may lead to severe disability and comorbidity. Despite breakthroughs …

Characterization of crystalline polymorphs and their quantitation has become an integral
part of the preclinical drug development process. Raman spectroscopy is a powerful …

Sulindac, a non-steroidal anti-inflammatory of the indene acetic acid class, was immobilized
inside layered double hydroxide Mg2Al and Zn2Al (LDH) nanovessels through a one pot …

The phase-selective crystallization of acetaminophen (ACM) using insoluble polymers as
heteronuclei was investigated in a combined experimental and computational effort to …