Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …

The Genetic Epidemiology of COPD (COPDGene) study is a noninterventional, multicenter,
longitudinal analysis of> 10,000 subjects, including smokers with a≥ 10 pack-year history …

Background Childhood asthma is strongly influenced by genetics and is a risk factor for
reduced lung function and chronic obstructive pulmonary disease (COPD) in adults. This …

Patients with concomitant features of asthma and chronic obstructive pulmonary disease
(COPD) have a heavy disease burden. Using data collected prospectively in the European …

Background Asthma is a significant worldwide health issue affecting kids and adults. Asthma
management is mainly straightforward, but considering the associated co-morbidities, it is …

Introduction Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome
and may comprise several different phenotypes that are driven by different molecular …

Background Anti-eosinophilic therapy with interleukin-5/interleukin-5-receptor antibodies
represents an established treatment for patients with severe eosinophilic asthma (SEA) but …

The concept that the small airway is a primary pathological site for all COPD phenotypes has
been challenged by recent findings that the disease starts from the central airways in COPD …

Background Two spirometry criteria have been proposed for early chronic obstructive
pulmonary disease (COPD) in young smokers: 1) forced expiratory volume in 1 s (FEV …

The many faces of asthma-chronic obstructive pulmonary disea... : Current Opinion in
Pulmonary Medicine The many faces of asthma-chronic obstructive pulmonary disease overlap …