Background Metabolic syndromes are the multi-metabolic abnormality characterized by
hyperlipidemia, obesity, hyperglycemia, diabetes, hypertension, cardiovascular disease …

Metformin has been widely used as a first-line anti-diabetic medicine for the treatment of
type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses …

Background Our previous preclinical study showed that the extract mixture (EM) of
Andrographis paniculata (Burm. f.) Wall. ex Nees (AP) and Syzygium polyanthum (Wight.) …

Objective: To report a case of idiosyncratic hepatotoxicity associated with metformin in the
treatment of type 2 diabetes with nonalcoholic fatty liver disease (NAFLD). Case Summary: A …

Abstract Introduction and Objectives There is increasing evidence to suggest that
therapeutic doses of metformin are unlikely to cause lactic acidosis. The aims of this …

Accumulating studies implicate that the metformin (MET)-and oligofructose (OFS)-altered gut
microbiota may play roles in the improvement of type 2 diabetes mellitus (T2DM) and …

Introduction Metformin is a first-line drug choice for the treatment of type 2 diabetes mellitus
(DM-2). Metformin-induced hepatotoxicity has rarely been reported. We report on a case of …

Background: Knowledge of metformin-induced hepatotoxicity is based on case reports. The
aim of this study was to investigate the clinical features of metformin-induced hepatotoxicity …

The use of human and veterinary drugs has led to the accumulation of pharmaceuticals in
various aquatic environments at progressively increasing levels, exhibiting strong ecological …

This is a case report of a 44-year-old obese female who developed subclinical hepatic injury
4 weeks after starting metformin for type 2 diabetes. She had a rise in her alanine …