High dietary fructose: direct or indirect dangerous factors disturbing tissue and organ functions

DM Zhang, RQ Jiao, LD Kong - Nutrients, 2017 - mdpi.com
High dietary fructose is a major contributor to insulin resistance and metabolic syndrome,
disturbing tissue and organ functions. Fructose is mainly absorbed into systemic circulation …

High fructose diet-induced metabolic syndrome: pathophysiological mechanism and treatment by traditional Chinese medicine

Y Pan, LD Kong - Pharmacological research, 2018 - Elsevier
Fructose is a natural monosaccharide broadly used in modern society. Over the past few
decades, epidemiological studies have demonstrated that high fructose intake is an …

High‐fructose diet increases inflammatory cytokines and alters gut microbiota composition in rats

Y Wang, W Qi, G Song, S Pang, Z Peng… - Mediators of …, 2020 - Wiley Online Library
High‐fructose diet induced changes in gut microbiota structure and function, which have
been linked to inflammatory response. However, the effect of small or appropriate doses of …

Fructose induces visceral adipose tissue inflammation and insulin resistance even without development of obesity in adult female but not in male rats

S Kovačević, J Brkljačić, D Vojnović Milutinović… - Frontiers in …, 2021 - frontiersin.org
Introduction: Obesity and related metabolic disturbances are frequently related to modern
lifestyle and are characterized by excessive fructose intake. Visceral adipose tissue (VAT) …

β-Cryptoxanthin ameliorates metabolic risk factors by regulating NF-κB and Nrf2 pathways in insulin resistance induced by high-fat diet in rodents

K Sahin, C Orhan, F Akdemir, M Tuzcu, N Sahin… - Food and Chemical …, 2017 - Elsevier
The aim of this experiment was to determine the effects of β-cryptoxanthin (BCX) on the
cardiometabolic health risk factors and NF-κB and Nrf2 pathway in insulin resistance …

Oxidative stress linking obesity and cancer: is obesity a 'Radical trigger'to Cancer?

M Jovanović, S Kovačević, J Brkljačić… - International Journal of …, 2023 - mdpi.com
Obesity is on the rise worldwide, and consequently, obesity-related non-communicable
diseases are as well. Nutritional overload induces metabolic adaptations in an attempt to …

Oxidative stress in obesity and insulin resistance

A Panic, J Stanimirovic… - Exploration of …, 2022 - explorationpub.com
Since obesity is one of the main factors in the development of insulin resistance (IR) and is
also associated with increased oxidative stress (OxS) rate, this study aims to review the …

[HTML][HTML] Peel flour of Passiflora edulis Var. Flavicarpa supplementation prevents the insulin resistance and hepatic steatosis induced by low-fructose-diet in young rats

MJ Goss, MLO Nunes, ID Machado, L Merlin… - Biomedicine & …, 2018 - Elsevier
The increase in fructose consumption in the last decades has an important correlation with
the growth of overweight population. Fructose is a monosaccharide found in fruits …

KRIT1 deficiency promotes aortic endothelial dysfunction

F Vieceli Dalla Sega, R Mastrocola, G Aquila… - International Journal of …, 2019 - mdpi.com
Loss-of-function mutations of the gene encoding Krev interaction trapped protein 1 (KRIT1)
are associated with the pathogenesis of Cerebral Cavernous Malformation (CCM), a major …

The depressogenic potential of added dietary sugars

DJ Reis, SS Ilardi, MS Namekata, EK Wing… - Medical hypotheses, 2020 - Elsevier
Added sugars are ubiquitous in contemporary Western diets. Although excessive sugar
consumption is now robustly associated with an array of adverse health consequences …