Urinary markers of tubular injury in early diabetic nephropathy

T Fiseha, Z Tamir - International journal of nephrology, 2016 - Wiley Online Library
Diabetic nephropathy (DN) is a common and serious complication of diabetes associated
with adverse outcomes of renal failure, cardiovascular disease, and premature mortality …

Glabridin, a bioactive component of licorice, ameliorates diabetic nephropathy by regulating ferroptosis and the VEGF/Akt/ERK pathways

H Tan, J Chen, Y Li, Y Li, Y Zhong, G Li, L Liu, Y Li - Molecular Medicine, 2022 - Springer
Abstract Background Glabridin (Glab) is a bioactive component of licorice that can
ameliorate diabetes, but its role in diabetic nephropathy (DN) has seldom been reported …

[HTML][HTML] Evaluation of kidney injury molecule-1 as a disease progression biomarker in diabetic nephropathy

FA Khan, SS Fatima, GM Khan… - Pakistan journal of …, 2019 - ncbi.nlm.nih.gov
Methods: This follow-up study included n= 85 subjects from the diabetic clinic of Jinnah Post
Graduate Medical Center (JPMC) in collaboration with Aga Khan University from November …

Biomarkers and signaling pathways of diabetic nephropathy and peripheral neuropathy: Possible therapeutic intervention of rutin and quercetin

TF Roohi, S Mehdi, S Aarfi, KL Krishna, S Pathak… - Diabetology …, 2024 - Springer
Diabetic nephropathy and peripheral neuropathy are the two main complications of chronic
diabetes that contribute to high morbidity and mortality. These conditions are characterized …

Uninephrectomized high‐fat‐Fed Nicotinamide‐Streptozotocin‐Induced Diabetic Rats: A model for the investigation of diabetic nephropathy in Type 2 diabetes

VK Bayrasheva, AY Babenko… - Journal of diabetes …, 2016 - Wiley Online Library
Type 2 diabetes (DM2) could be reproduced in rats with alimentary obesity by using low
doses of streptozotocin (LD‐STZ) as well as STZ in high doses with preliminary nicotinamide …

Association of urinary monocyte chemoattractant protein-1 (MCP-1) and kidney injury molecule-1 (KIM-1) with risk factors of diabetic kidney disease in type 2 diabetes …

K Siddiqui, SS Joy, K Al-Rubeaan - International urology and nephrology, 2019 - Springer
Purpose Urinary kidney injury molecule-1 and monocyte chemoattractant protein-1 are
significance factors in the diagnosis and intervention of diabetic kidney diseases. This study …

Biomarkers for Diabetic Nephropathy with a Focus on Kidney Injury Molecule-1 (KIM-1)

F Khonsha, M Valilo, HR Nejabati… - Current diabetes …, 2024 - ingentaconnect.com
Diabetic Nephropathy (DN), with an increasing rate of mortality and morbidity, is considered
the main cause of End-Stage Renal Disease (ESRD). A wide spectrum of biomarkers exist …

Kidney injury molecule-1; is it a predictive marker for renal diseases?

DG Anandkumar, PC Dheerendra… - Journal of …, 2023 - jnephropharmacology.com
Kidney injury is the main cause of mortality and morbidity globally. The kidney injury
molecule (KIM-1) is a type 1 transmembrane protein, which is been upregulated during renal …

Diagnostic performance of biomarkers urinary KIM-1 and YKL-40 for early diabetic nephropathy, in patients with type 2 diabetes: a systematic review and meta …

GV Kapoula, PI Kontou, PG Bagos - Diagnostics, 2020 - mdpi.com
There is a lack of prediction markers for early diabetic nephropathy (DN) in patients with type
2 diabetes mellitus (T2DM). The aim of this systematic review and meta-analysis was to …

Does serum kidney injury molecule-1 predict early diabetic nephropathy: A comparative study with microalbuminuria

D Balu, V Krishnan, V Krishnamoorthy… - Annals of African …, 2022 - journals.lww.com
Objective: The present study aimed to investigate the usefulness of serum KIM-1 as an early
marker of DN. Patients and Methods: The present study included total 75 participants …