Prostate cancer is the second most diagnosed cancer of men all over the world. In the last
few decades, new imaging techniques based on Magnetic Resonance Imaging (MRI) have …

Trust region methods are a class of numerical methods for optimization. Unlike line search
type methods where a line search is carried out in each iteration, trust region methods …

A comprehensive and unified account of the neural computations underlying speech
production, offering a theoretical framework bridging the behavioral and the neurological …

Contemporary global optimization algorithms are based on local measures of utility, rather
than a probability measure over location and value of the optimum. They thus attempt to …

The time it takes a bound electron to respond to the electromagnetic force of light sets a
fundamental speed limit on the dynamic control of matter and electromagnetic signal …

Optogenetics is the genetic approach for controlling cellular processes with light. It provides
spatiotemporal, quantitative and reversible control over biological signaling and metabolic …

Background Extant data from in vivo animal models and postmortem studies indicate that
Alzheimer's disease (AD) pathology is associated with reduction of the brain antioxidant …

The design and implementation of a new algorithm for solving large nonlinear programming
problems is described. It follows a barrier approach that employs sequential quadratic …

The field of inverse problems has experienced explosive growth in the last few decades.
This is due in part to the importance of applications, like biomedical and seismic imaging …

An algorithm for minimizing a nonlinear function subject to nonlinear inequality constraints is
described. It applies sequential quadratic programming techniques to a sequence of barrier …