Hydroxychloroquine (HCQ; Plaquenil) is used increasingly in the management of a variety of
autoimmune disorders, with well established roles in dermatology and rheumatology and …

The discovery of the necroptosis, a form of regulated necrosis that is mediated by receptor-
interacting protein kinase 1 (RIPK1), RIPK3, and mixed-lineage kinase domain-like …

Lysosome is a ubiquitous acidic organelle fundamental for the turnover of unwanted cellular
molecules, particles, and organelles. Currently, the pivotal role of lysosome in regulating cell …

Pyroptosis is mainly considered as a new pro-inflammatory mediated-programmed cell
death. In addition, pyroptosis is described by gasdermin-induced pore formation on the …

The development of novel, highly efficient, reliable, and robust surface enhanced Raman
scattering (SERS) substrates containing a large number of hot spots with programmed size …

Methods: A novel niosomal formulation of tamoxifen-curcumin with Span 80 and lipid to drug
ratio of 20 was employed. The MCF-7 cells were cultured and then treated with IC 50 value …

While the development of anti-vascular endothelial growth factor (anti-VEGF) as a therapy
for neovascular age-related macular degeneration (AMD) was a great success, the …

Mechanical feedback from the tumor microenvironment regulates an array of processes
underlying cancer biology. For example, increased stiffness of mammary extracellular matrix …

Purpose: Accumulation of oxidized phospholipids/lipoproteins with age is suggested to
contribute to the pathogenesis of AMD. We investigated the effect of oxidized LDL (ox-LDL) …

Introduction: Designing and developing drug delivery systems has received tremendous
attention during the last decade. The treatment of cancer cells is a complicated process due …