There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

Gastric cancer is one of the most common malignant tumours worldwide. Genetic and
epigenetic alterations are key factors in gastric carcinogenesis and drug resistance to …

DNA single‐strand breaks (SSBs) disrupt DNA replication and induce chromosome
breakage. However, whether SSBs induce chromosome breakage when present behind …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) dysregulates antiviral
signaling, immune response, and cell metabolism in human body. Viral genome and …

Introduction Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast
cancer with a high risk of distant metastasis, an extremely poor prognosis, and a high risk of …

Two series of new tetrahydropyrimidine (THPM)-1, 2, 3-triazole clubbed compounds were
designed, synthesized and screened for their antitubercular (anti-TB) activity against M …

Background Type II testicular germ cell tumours (TGCT) are the most prevalent tumours in
young men. Patients suffering from cisplatin-resistant TGCTs are facing very poor prognosis …

Background The dual marker algorithm Risk of Ovarian Malignancy Algorithm (ROMA) has
been widely used in the clinic for the identification of equivocal pelvic masses in ovarian …

The worldwide burden of cancers is increasing at a very high rate, including the aggressive
and resistant forms of cancers. Certain levels of breakthrough have been achieved with the …

Prostate cancer (PCa) is a common urinary malignancy. The lack of specific and sensitive
biomarkers for the early diagnosis and prognosis of PCa makes it important to seek …