Keratins are the type I and II intermediate filament proteins which form a cytoskeletal network
within all epithelial cells. They are expressed in pairs in a tissue-and differentiation-specific …

Keratins are heteropolymeric proteins which form the intermediate filament cytoskeleton in
epithelial cells. Since 1991, mutations in several keratin genes have been found to cause a …

During organogenesis, the middle to caudal portion of Müllerian epithelium differentiates
into uterine and vaginal epithelia in females. Functional differentiation of uterine and vaginal …

Diabetic foot ulcers (DFU) are one of the most common diabetes-related cause of
hospitalization and often lead to severe infections and poor healing. It has been recently …

Cells and tissues sense, respond to and translate mechanical forces into biochemical
signals through mechanotransduction, which governs individual cell responses that drive …

BACKGROUND: Foot ulcers are one of the main diabetes complications due to its high
frequency and difficulty of complete healing. There are several factors that participate in …

Diabetic foot ulcers (DFUs) are chronic wounds with high matrix metalloproteinase (MMP)
activity, and are a frequent complication on diabetics. This work studied the expression of …

Keratin intermediate filaments play an important role in maintaining the integrity of the skin
structure. Understanding the importance of this subject is possible with the investigation of …

Foot ulceration is one of the most common and complex sequelae of diabetes mellitus,
generally posing a therapeutic challenge due to poor healing responses and high rates of …

Background Basal epidermolysis bullosa simplex (EBS) is a hereditary skin blistering
disorder resulting in most cases from missense mutations in the keratin 5 (KRT5) or keratin …