Metal ions are inextricably associated with RNAs of any size and control their folding and
activity to a large part. In order to understand RNA mechanisms, also the positioning …

Since the 1980s, several small RNA motifs capable of chemical catalysis have been
discovered. These small ribozymes, composed of between approximately 40 and 200 …

Nickel is a highly important metal, and the detection of Ni 2+ using biosensors is a long-
stand analytical challenge. DNA has been widely used for metal detection, although no DNA …

Volume 17, entitled Lead: Its Effects on Environment and Health of the series Metal Ions in
Life Sciences centers on the interrelations between biosystems and lead. The book provides …

Studies on RNA motifs capable of binding metal ions have largely focused on Mg2+-specific
motifs, therefore information concerning interactions of other metal ions with RNA is still very …

The spinach family of RNA aptamers are RNA mimics of green fluorescent protein (GFP) that
have previously been designed to address the challenges of imaging RNA inside living …

Electron paramagnetic resonance (EPR) spectroscopy was used to examine changes in
internal structure and dynamics of the hammerhead ribozyme upon metal ion induced …

Functionally critical metals interact with RNA through complex coordination schemes that
are currently difficult to visualize at the atomic level under solution conditions. Here, we …

Divalent Mg 2+ ions often serve as cofactors in enzyme or ribozyme-catalyzed phosphoryl
transfer reactions. In this work, the interaction of Mg 2+ ions and di-metal bridge complexes …

Nucleic acids are responsible for the storage, transmission, and expression of genetic
information in all living organisms. These macromolecules tend to behave as salts in …