Fluorescent amino acids as versatile building blocks for chemical biology

Z Cheng, E Kuru, A Sachdeva, M Vendrell - Nature Reviews Chemistry, 2020 - nature.com
Fluorophores have transformed the way we study biological systems, enabling non-invasive
studies in cells and intact organisms, which increase our understanding of complex …

A photo-cross-linking approach to monitor protein dynamics in living cells

R Miyazaki, Y Akiyama, H Mori - … Et Biophysica Acta (BBA)-General Subjects, 2020 - Elsevier
Background Proteins, which comprise one of the major classes of biomolecules that
constitute a cell, interact with other cellular factors during both their biogenesis and …

Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase

L Davis, I Radman, A Goutou, A Tynan, K Baxter, Z Xi… - Elife, 2021 - elifesciences.org
Synthetic strategies for optically controlling gene expression may enable the precise
spatiotemporal control of genes in any combination of cells that cannot be targeted with …

Using a quadruplet codon to expand the genetic code of an animal

Z Xi, L Davis, K Baxter, A Tynan, A Goutou… - Nucleic Acids …, 2022 - academic.oup.com
Genetic code expansion in multicellular organisms is currently limited to the use of
repurposed amber stop codons. Here, we introduce a system for the use of quadruplet …

Isolation and molecular identification of nematode surface mutants with resistance to bacterial pathogens

D O'Rourke, MJ Gravato-Nobre, D Stroud… - G3: Genes …, 2023 - academic.oup.com
Numerous mutants of the nematode Caenorhabditis elegans with surface abnormalities
have been isolated by utilizing their resistance to a variety of bacterial pathogens …

Optically splitting symmetric neuron pairs in C. elegans

L Davis, I Radman, A Goutou, A Tynan, K Baxter, Z Xi… - bioRxiv, 2020 - biorxiv.org
Two thirds of the 302 neurons in C. elegans form bilaterally symmetric pairs in its physical
connectome, and similar gross morphological symmetries are seen in the nervous systems …

Synthetic methodology in chemical biology

RC Brewster, S Wallace - Biomolecular and Bioanalytical …, 2019 - Wiley Online Library
This chapter will explore the diversity of modern synthetic methods available to practitioners
in the ever‐expanding field of chemical biology. The chapter begins by providing a general …

Contribution of actin cytoskeleton to C. elegans embryonic elongation

A Lardennois - 2019 - theses.hal.science
Body axis elongation is a fundamental morphogenetic process, involving cell shape
changes powered by mechanical forces through small incremental steps which need to be …

Tools for connectomics in C. elegans

NC Barry - 2018 - dspace.mit.edu
Efforts to model computation in biological neural networks require knowledge of the
structure of the network, the dynamics that play across it, and a network simple enough to be …