Polypharmacy: evaluating risks and deprescribing

AD Halli-Tierney, C Scarbrough, D Carroll - American family physician, 2019 - aafp.org
Polypharmacy, defined as regular use of at least five medications, is common in older adults
and younger at-risk populations and increases the risk of adverse medical outcomes. There …

Deprescribing: a narrative review of the evidence and practical recommendations for recognizing opportunities and taking action

E Reeve, W Thompson, B Farrell - European journal of internal medicine, 2017 - Elsevier
Deprescribing can be defined as the process of withdrawal or dose reduction of medications
which are considered inappropriate in an individual. The aim of this narrative review is to …

Too much medicine in older people? Deprescribing through shared decision making

J Jansen, V Naganathan, SM Carter, AJ McLachlan… - Bmj, 2016 - bmj.com
Too much medicine in older people? Deprescribing through shared decision making Page 1 Too
much medicine in older people? Deprescribing through shared decision making Jansen and …

Assessment of attitudes toward deprescribing in older Medicare beneficiaries in the United States

E Reeve, JL Wolff, M Skehan, EA Bayliss… - JAMA internal …, 2018 - jamanetwork.com
Importance Use of harmful and/or unnecessary medications in older adults is prevalent. This
can lead to avoidable harms such as adverse drug reactions, falls, hospitalization, and …

Barriers and facilitators to deprescribing in primary care: a systematic review

AJ Doherty, P Boland, J Reed, AJ Clegg, AM Stephani… - BJGP open, 2020 - bjgpopen.org
Background Managing polypharmacy is a challenge for healthcare systems globally. It is
also a health inequality concern as it can expose some of the most vulnerable in society to …

Development and validation of the revised patients' attitudes towards deprescribing (rPATD) questionnaire: versions for older adults and caregivers

E Reeve, LF Low, S Shakib, SN Hilmer - Drugs & aging, 2016 - Springer
Background Knowledge of consumer (patient and caregiver) attitudes is essential for
conducting medication optimization in practice. Objectives The aim of this study was to …

Decision-making preferences and deprescribing: perspectives of older adults and companions about their medicines

K Weir, B Nickel, V Naganathan… - The Journals of …, 2018 - academic.oup.com
Objectives Polypharmacy in the older population is increasing—and can be harmful. It can
be safe to reduce or carefully cease medicines (deprescribing) but a collaborative approach …

Beliefs and attitudes of older adults and carers about deprescribing of medications: a qualitative focus group study

E Reeve, LF Low, SN Hilmer - British Journal of General Practice, 2016 - bjgp.org
Background Deprescribing describes the complex process that is required for the safe and
effective cessation of medications that are likely to cause more harm than benefit …

An adaptable framework for factors contributing to medication adherence: results from a systematic review of 102 conceptual frameworks

KQE Peh, YH Kwan, H Goh, H Ramchandani… - Journal of general …, 2021 - Springer
Objective To summarize the available conceptual models for factors contributing to
medication adherence based on the World Health Organization (WHO)'s five dimensions of …

A systems approach to identifying the challenges of implementing deprescribing in older adults across different health-care settings and countries: a narrative review

M Sawan, E Reeve, J Turner, A Todd… - Expert review of …, 2020 - Taylor & Francis
Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …