Microbial serine protease inhibitors and their therapeutic applications

BS Harish, KB Uppuluri - International journal of biological …, 2018 - Elsevier
Serine protease inhibitors, inhibit serine proteases either partially or completely after forming
complexes with their respective proteases. Protease actions are significant for many …

Biogenic Synthesis of Silver Nanoparticles Using Streptomyces spp. and their Antifungal Activity Against Fusarium verticillioides

K Marathe, J Naik, V Maheshwari - Journal of Cluster Science, 2021 - Springer
The present study reports the synthesis of silver nanoparticles (AgNPs) using
haloalkaliphilic Streptomyces spp. characterization, and antifungal activity thereof. The UV …

Insecticidal potential of endophytic Streptomyces sp. against Zeugodacus cucurbitae (Coquillett)(Diptera: Tephritidae) and biosafety evaluation

S Devi, J Verma, SK Sohal, RK Manhas - Toxicon, 2023 - Elsevier
Fruit flies of Tephritidae family pose a serious threat to cultivation of fruits and vegetables
across the world. Among them, melon fruit fly, Zeugodacus cucurbitae (Coquillett)(Diptera …

Protease inhibitors and their applications: An overview

KR Marathe, RH Patil, KS Vishwakarma… - Studies in natural …, 2019 - Elsevier
This chapter describes the various sources (with an emphasis on microbial sources),
classification, mechanisms of inhibition, purification, characterization, and applications of …

Characterization of a Bowman–Birk type trypsin inhibitor purified from seeds of Solanum surattense

AP Herwade, SS Kasar, NR Rane, S Ahmed… - Scientific reports, 2021 - nature.com
A Bowman–Birk type trypsin inhibitor protein (SSTI) from seeds of the medicinal plant
Solanum surattense was isolated, purified and characterized. SSTI showed a single band on …

[HTML][HTML] Purification and characterization of a protease from the visceral mass of Mytella charruana and its evaluation to obtain antimicrobial peptides

LP Dornelles, MFD de Souza, PM da Silva… - Food chemistry, 2018 - Elsevier
This work describes purification of a protease from the visceral mass of the mussel Mytella
charruana as well as evaluation of its ability to hydrolyze milk casein to generate …

In vivo developmental studies of Helicoverpa armigera and in silico molecular interactions with trypsin reveal the bio-insecticidal potential of trypsin inhibitor (SSTI) …

AP Herwade, SS Barale, KD Sonawane… - International Journal of …, 2022 - Elsevier
We report the impact of gut protease inhibition on the development of Helicoverpa armigera
by trypsin inhibitor and the use of molecular modeling to understand the mechanism of …

Synthesis, characterisation and in vitro anticancer activity of conjugated protease inhibitor–silver nanoparticles (AgNPs–PI) against human breast MCF-7 and prostate …

K Marathe, J Naik, V Maheshwari - Bioprocess and Biosystems …, 2024 - Springer
The conjugated silver nanoparticles using biomolecules have attracted great attention of
researchers because physical dimensions and surface chemistry play important roles in …

A new thermostable rhizopuspepsin: Purification and biochemical characterisation

CV Chinmayee, A Martin, BSG Kumar, SA Singh - Process Biochemistry, 2022 - Elsevier
The new thermostable fungal aspartic protease was produced through solid-state
fermentation from Rhizopus azygosporus (MTCC 10195). The protease was purified by a …

[HTML][HTML] Unraveling a natural protease inhibitor from marine Streptomyces griseoincarnatus HK12 active against Chikungunya virus

N Kamarudheen, A Khaparde, S Gopal… - Microbiological Research, 2021 - Elsevier
Proteases play an indispensable role in the life cycles of several life-threatening organisms
such as the ones causing malaria, cancer and AIDS. A targeted blockade of these enzymes …