Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

KD Davis, N Aghaeepour, AH Ahn, MS Angst… - Nature Reviews …, 2020 - nature.com
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Challenges of neuropathic pain: focus on diabetic neuropathy

DC Rosenberger, V Blechschmidt… - Journal of Neural …, 2020 - Springer
Neuropathic pain is a frequent condition caused by a lesion or disease of the central or
peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain …

[HTML][HTML] Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments

S Tesfaye, AJM Boulton, PJ Dyck, R Freeman… - Diabetes …, 2010 - ncbi.nlm.nih.gov
Preceding the joint meeting of the 19th annual Diabetic Neuropathy Study Group of the
European Association for the Study of Diabetes (NEURODIAB) and the 8th International …

NeuPSIG guidelines on neuropathic pain assessment

M Haanpää, N Attal, M Backonja, R Baron, M Bennett… - PAIN®, 2011 - Elsevier
This is a revision of guidelines, originally published in 2004, for the assessment of patients
with neuropathic pain. Neuropathic pain is defined as pain arising as a direct consequence …

New perspective in diabetic neuropathy: from the periphery to the brain, a call for early detection, and precision medicine

H Yang, G Sloan, Y Ye, S Wang, B Duan… - Frontiers in …, 2020 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …

Advances in screening, early diagnosis and accurate staging of diabetic neuropathy

J Carmichael, H Fadavi, F Ishibashi… - Frontiers in …, 2021 - frontiersin.org
The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …

European Federation of Neurological Societies/Peripheral Nerve Society Guideline on the use of skin biopsy in the diagnosis of small fiber neuropathy. Report of a …

G Lauria, ST Hsieh, O Johansson… - European journal of …, 2010 - Wiley Online Library
Background: Revision of the guidelines on the use of skin biopsy in the diagnosis of
peripheral neuropathy, published in 2005, has become appropriate owing to publication of …

A new look at painful diabetic neuropathy

G Sloan, P Shillo, D Selvarajah, J Wu… - Diabetes research and …, 2018 - Elsevier
The prevalence of diabetes mellitus and its chronic complications continue to increase
alarmingly. Consequently, the massive expenditure on diabetic distal symmetrical …

EFNS guidelines on neuropathic pain assessment: revised 2009

G Cruccu, C Sommer, P Anand, N Attal… - European journal of …, 2010 - Wiley Online Library
Background and purpose: We have revised the previous EFNS guidelines on neuropathic
pain (NP) assessment, which aimed to provide recommendations for the diagnostic process …

Early detection of diabetic peripheral neuropathy: a focus on small nerve fibres

J Burgess, B Frank, A Marshall, RS Khalil, G Ponirakis… - Diagnostics, 2021 - mdpi.com
Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …