[HTML][HTML] Stem cells and cell therapies in lung biology and lung diseases

DJ Weiss, I Bertoncello, Z Borok, C Kim… - Proceedings of the …, 2011 - atsjournals.org
EXECUTIVE SUMMARY The University of Vermont College of Medicine and the Vermont
Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the …

MIF as a disease target: ISO-1 as a proof-of-concept therapeutic

Y Al-Abed, S VanPatten - Future medicinal chemistry, 2011 - Taylor & Francis
Macrophage migration inhibitory factor (MIF) is a pleiotropic proinflammatory cytokine that
has been implicated as playing a causative role in many disease states, including sepsis …

Macrophage migration inhibitory factor–CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors

S Lourenco, VH Teixeira, T Kalber, RJ Jose… - The Journal of …, 2015 - journals.aai.org
Mesenchymal stromal cells (MSCs) are inherently tumor homing and can be isolated,
expanded, and transduced, making them viable candidates for cell therapy. This tumor …

Clonal analysis of the proliferation potential of human bone marrow mesenchymal stem cells as a function of potency

KC Russell, MR Lacey, JK Gilliam… - Biotechnology and …, 2011 - Wiley Online Library
Human mesenchymal stem cells (MSCs) from bone marrow are a heterogeneous ensemble
of progenitors and lineage‐committed cells, with a broad range of regenerative properties …

Low-level shear stress induces human mesenchymal stem cell migration through the SDF-1/CXCR4 axis via MAPK signaling pathways

L Yuan, N Sakamoto, G Song, M Sato - Stem cells and development, 2013 - liebertpub.com
Mesenchymal stem cells (MSCs) are able to home and migrate into damaged tissues and
are thus, considered an optimal therapeutic strategy for clinical use. We previously …

Molecular profiles of cell‐to‐cell variation in the regenerative potential of mesenchymal stromal cells

KC O'Connor - Stem Cells International, 2019 - Wiley Online Library
Cell‐to‐cell variation in the regenerative potential of mesenchymal stromal cells (MSCs)
impedes the translation of MSC therapies into clinical practice. Cellular heterogeneity is …

[HTML][HTML] Decoy TRAIL receptor CD264: a cell surface marker of cellular aging for human bone marrow-derived mesenchymal stem cells

SD Madsen, KC Russell, HA Tucker, J Glowacki… - Stem cell research & …, 2017 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are a mixture of progenitors that are
heterogeneous in their regenerative potential. Development of MSC therapies with …

Molecular targeting regulation of proliferation and differentiation of the bone marrow-derived mesenchymal stem cells or mesenchymal stromal cells

BY Chen, X Wang, LW Chen, ZJ Luo - Current drug targets, 2012 - ingentaconnect.com
The bone marrow-derived mesenchymal stem cells or mesenchymal stromal cells (MSCs),
with pluripotent differentiation capacity, present an ideal source for cell transplantation or …

Cell-surface expression of neuron-glial antigen 2 (NG2) and melanoma cell adhesion molecule (CD146) in heterogeneous cultures of marrow-derived mesenchymal …

KC Russell, HA Tucker, BA Bunnell… - … Engineering Part A, 2013 - liebertpub.com
Cellular heterogeneity of mesenchymal stem cells (MSCs) impedes their use in regenerative
medicine. The objective of this research is to identify potential biomarkers for the enrichment …

[HTML][HTML] Mitigation of lethal radiation syndrome in mice by intramuscular injection of 3D cultured adherent human placental stromal cells

E Gaberman, L Pinzur, L Levdansky, M Tsirlin… - PloS one, 2013 - journals.plos.org
Exposure to high lethal dose of ionizing radiation results in acute radiation syndrome with
deleterious systemic effects to different organs. A primary target is the highly sensitive bone …