Alzheimer's disease (AD) is the most prevalent form of dementia. The exact pathophysiology
of this disease remains incompletely understood and safe and effective therapies are …

Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Vitamin D is a fat-soluble secosteroid, traditionally considered a key regulator of bone
metabolism, calcium and phosphorous homeostasis. Its action is made possible through the …

Acquiring the recommended daily allowance of vitamins is crucial for maintaining
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …

Vitamin D deficiency has been epidemiologically linked to Alzheimer's disease (AD) and
other dementias, but no interventional studies have proved causality. Our previous work …

Ageing can occur at different rates, but what controls this variable rate is unknown. Here I
have developed a hypothesis that vitamin D may act to control the rate of ageing. The basis …

The ApoE4 allele is the most well-studied genetic risk factor for Alzheimer's disease, a
condition that is increasing in prevalence and remains without a cure. Precision nutrition …

Nuclear receptors, also known as ligand-activated transcription factors, regulate gene
expression upon ligand signals and present as attractive therapeutic targets especially in …

Neurological disorders are the major cause of disability, leading to a decrease in quality of
life by impairing cognitive, sensorimotor, and motor functioning. Several factors have been …