Engineered nanomaterials: From their properties and applications, to their toxicity towards marine bivalves in a changing environment

L De Marchi, F Coppola, AMVM Soares, C Pretti… - Environmental …, 2019 - Elsevier
As a consequence of their unique characteristics, the use of Engineered Nanomaterials
(ENMs) is rapidly increasing in industrial, agricultural products, as well as in environmental …

Redox mechanisms in migraine: novel therapeutics and dietary interventions

P Ferroni, P Barbanti, D Della-Morte… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Migraine represents the third most prevalent and the seventh most disabling
human disorder. Approximately 30% of migraine patients experience transient, fully …

Lenti‐GDNF gene therapy protects against Alzheimer's disease‐like neuropathology in 3xTg‐AD mice and MC65 cells

S Revilla, S Ursulet, MJ Álvarez‐López… - CNS neuroscience & …, 2014 - Wiley Online Library
Aims Glial cell‐derived neurotrophic factor (GDNF) is emerging as a potent neurotrophic
factor with therapeutic potential against a range of neurodegenerative conditions including …

Transcriptional profile of genes involved in oxidative stress and antioxidant defense in PC12 cells following treatment with cerium oxide nanoparticles

G Ciofani, GG Genchi, B Mazzolai, V Mattoli - Biochimica et Biophysica Acta …, 2014 - Elsevier
Background Thanks to their impressive catalytic properties, cerium oxide nanoparticles
(nanoceria) are able to mimic the activity of superoxide dismutase and of catalase, therefore …

Shikonin protects dopaminergic cell line PC12 against 6-hydroxydopamine-mediated neurotoxicity via both glutathione-dependent and independent pathways and by …

E Esmaeilzadeh, M Gardaneh, E Gharib… - Neurochemical …, 2013 - Springer
We have investigated the mechanism of shikonin function on protection of dopaminergic
neurons against 6-OHDA-induced neurotoxicity. Treatment of rat pheochromocytoma cell …

Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 …

HN Mai, LTT Nguyen, EJ Shin, DJ Kim… - Free Radical Biology …, 2019 - Elsevier
Compelling evidence indicates that oxidative stress contributes to cocaine neurotoxicity. The
present study was performed to elucidate the role of the glutathione peroxidase-1 (GPx-1) in …

Co-treatment with sulforaphane and nano-metformin molecules accelerates apoptosis in HER2+ breast cancer cells by inhibiting key molecules

A Keshandehghan, S Nikkhah… - Nutrition and …, 2020 - Taylor & Francis
Breast cancer cell lines MCF-10, MCF-7 and BT-474 expressing various levels of HER2
were examined for their response to treatment with sulforaphane (SLFN), metformin (MTFN) …

Dopaminergic induction of umbilical cord mesenchymal stem cells by conditioned medium of choroid plexus epithelial cells reduces apomorphine-induced rotation in …

A Aliaghaei, M Gardaneh, N Maghsoudi… - Archives of Iranian …, 2016 - journalaim.com
BACKGROUND/OBJECTIVE: Degeneration of dopaminergic neurons in Parkinson's
disease (PD) implies cell replacement using potentially differentiable sources as a …

Effects of anthocyanidins on myogenic differentiation and antioxidant defense in primary myogenic cells isolated from rainbow trout (Oncorhynchus mykiss)

A Villasante, MS Powell, K Moutou, GK Murdoch… - Aquaculture, 2016 - Elsevier
There is increasing interest in using plant-derived extracts to promote growth and health in
finfish species in recent years. Elucidating the effects of plant secondary metabolites on …

GDNF induces RET–SRC–HER2-dependent growth in trastuzumab-sensitive but SRC-independent growth in resistant breast tumor cells

M Gardaneh, S Shojaei, A Kaviani… - Breast cancer research and …, 2017 - Springer
We investigated the role of glial cell line-derived neurotrophic factor (GDNF) in
compensating trastuzumab (TZMB)-induced apoptosis in HER2+ breast cancer (BC) cells …