[HTML][HTML] Brain (re) organisation following amputation: Implications for phantom limb pain

TR Makin, H Flor - Neuroimage, 2020 - Elsevier
Following arm amputation the region that represented the missing hand in primary
somatosensory cortex (S1) becomes deprived of its primary input, resulting in changed …

Convergent models of handedness and brain lateralization

RL Sainburg - Frontiers in psychology, 2014 - frontiersin.org
The pervasive nature of handedness across human history and cultures is a salient
consequence of brain lateralization. This paper presents evidence that provides a structure …

Stability of sensory topographies in adult cortex

TR Makin, SJ Bensmaia - Trends in cognitive sciences, 2017 - cell.com
Textbooks teach us that the removal of sensory input to sensory cortex, for example,
following arm amputation, results in massive reorganisation in the adult brain. In this opinion …

Revealing the neural fingerprints of a missing hand

S Kikkert, J Kolasinski, S Jbabdi, I Tracey… - Elife, 2016 - elifesciences.org
The hand area of the primary somatosensory cortex contains detailed finger topography,
thought to be shaped and maintained by daily life experience. Here we utilise phantom …

Is an artificial limb embodied as a hand? Brain decoding in prosthetic limb users

RO Maimon-Mor, TR Makin - PLoS Biology, 2020 - journals.plos.org
The potential ability of the human brain to represent an artificial limb as a body part
(embodiment) has been inspiring engineers, clinicians, and scientists as a means to …

[HTML][HTML] Relationship between chronic pain and brain reorganization after deafferentation: A systematic review of functional MRI findings

CR Jutzeler, A Curt, JLK Kramer - NeuroImage: Clinical, 2015 - Elsevier
Background Mechanisms underlying the development of phantom limb pain and
neuropathic pain after limb amputation and spinal cord injury, respectively, are poorly …

The homeostatic homunculus: rethinking deprivation-triggered reorganisation

D Muret, TR Makin - Current Opinion in Neurobiology, 2021 - Elsevier
Highlights•Homeostatic mechanisms may sustain persistent representation of a missing
hand.•Recent evidence indicates distributed latent activity across the homunculus.• …

Obtaining and maintaining cortical hand representation as evidenced from acquired and congenital handlessness

DB Wesselink, FMZ van den Heiligenberg, N Ejaz… - Elife, 2019 - elifesciences.org
A key question in neuroscience is how cortical organisation relates to experience.
Previously we showed that amputees experiencing highly vivid phantom sensations …

Upper limb activity in myoelectric prosthesis users is biased towards the intact limb and appears unrelated to goal-directed task performance

A Chadwell, L Kenney, MH Granat, S Thies, J Head… - Scientific reports, 2018 - nature.com
Studies of the effectiveness of prosthetic hands involve assessing user performance on
functional tasks, typically collected in the lab, sometimes combined with self-report of real …

Complex pattern of facial remapping in somatosensory cortex following congenital but not acquired hand loss

V Root, D Muret, M Arribas, E Amoruso, J Thornton… - Elife, 2022 - elifesciences.org
Cortical remapping after hand loss in the primary somatosensory cortex (S1) is thought to be
predominantly dictated by cortical proximity, with adjacent body parts remapping into the …