[HTML][HTML] Hematopoietic stem cells and their roles in tissue regeneration

JY Lee, SH Hong - International journal of stem cells, 2020 - synapse.koreamed.org
Hematopoietic stem cells (HSCs) are regarded as one of essential cell sources for treating
regenerative diseases. Among many stem cells, the feasibility of using adult-derived …

Anti-fibrogenic strategies and the regression of fibrosis

T Kisseleva, DA Brenner - Best practice & research Clinical …, 2011 - Elsevier
Liver fibrosis is an outcome of many chronic diseases, and often results in cirrhosis, liver
failure, and portal hypertension. Liver transplantation is the only treatment available for …

Granulocyte colony–stimulating factor mobilizes CD34+ cells and improves survival of patients with acute-on-chronic liver failure

V Garg, H Garg, A Khan, N Trehanpati, A Kumar… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Acute-on-chronic liver failure (ACLF) develops in patients with
chronic liver disease and has high mortality. Mobilization of bone marrow–derived stem cells …

Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I–II clinical trial

P Kharaziha, PM Hellström, B Noorinayer… - European journal of …, 2009 - journals.lww.com
Background End-stage liver disease is a medical problem with high morbidity and mortality.
We have investigated the feasibility, safety, and efficacy of using autologous mesenchymal …

Granulocyte colony-stimulating factor in severe alcoholic hepatitis: a randomized pilot study

V Singh, AK Sharma, LR Narasimhan… - Official journal of the …, 2014 - journals.lww.com
OBJECTIVES: Severe alcoholic hepatitis has high short-term mortality. The aim of this study
was to test the hypothesis that treatment of patients with alcoholic hepatitis with granulocyte …

[HTML][HTML] Granulocyte colony-stimulating factor and autologous CD133-positive stem-cell therapy in liver cirrhosis (REALISTIC): an open-label, randomised, controlled …

PN Newsome, R Fox, AL King, D Barton… - The Lancet …, 2018 - thelancet.com
Background Results of small-scale studies have suggested that stem-cell therapy is safe
and effective in patients with liver cirrhosis, but no adequately powered randomised …

[PDF][PDF] Granulocyte‐colony stimulating factor induces proliferation of hepatic progenitors in alcoholic steatohepatitis: a randomized trial

L Spahr, JF Lambert, L Rubbia‐Brandt… - …, 2008 - Wiley Online Library
Liver failure is the major cause of death in alcoholic steatohepatitis (ASH). In experimental
hepatitis, granulocyte‐colony stimulating factor (G‐CSF) mobilizes hematopoietic stem cells …

Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling

TG Bird, WY Lu, L Boulter… - Proceedings of the …, 2013 - National Acad Sciences
Tissue progenitor cells are an attractive target for regenerative therapy. In various organs,
bone marrow cell (BMC) therapy has shown promising preliminary results, but to date no …

[HTML][HTML] Phase 1 human trial of autologous bone marrow-hematopoietic stem cell transplantation in patients with decompensated cirrhosis

M Mohamadnejad, M Namiri, M Bagheri… - World journal of …, 2007 - ncbi.nlm.nih.gov
AIM: To evaluate safety and feasibility of autologous bone marrow-enriched CD34+
hematopoietic stem cell Tx through the hepatic artery in patients with decompensated …

Mobilized human hematopoietic stem/progenitor cells promote kidney repair after ischemia/reperfusion injury

B Li, A Cohen, TE Hudson, D Motlagh, DL Amrani… - Circulation, 2010 - Am Heart Assoc
Background—Understanding the mechanisms of repair and regeneration of the kidney after
injury is of great interest because there are currently no therapies that promote repair, and …