Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review

K Dąbrowska - Medicinal research reviews, 2019 - Wiley Online Library
Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …

Antibiotic resistance in Pseudomonas aeruginosa biofilms: towards the development of novel anti-biofilm therapies

PK Taylor, ATY Yeung, REW Hancock - Journal of biotechnology, 2014 - Elsevier
The growth of bacteria as structured aggregates termed biofilms leads to their protection
from harsh environmental conditions such as physical and chemical stresses, shearing …

Cryomicroneedles for transdermal cell delivery

H Chang, SWT Chew, M Zheng, DCS Lio… - Nature Biomedical …, 2021 - nature.com
Cell therapies for the treatment of skin disorders could benefit from simple, safe and efficient
technology for the transdermal delivery of therapeutic cells. Conventional cell delivery by …

Applications of bacteriophages versus phage enzymes to combat and cure bacterial infections: an ambitious and also a realistic application?

B Maciejewska, T Olszak, Z Drulis-Kawa - Applied microbiology and …, 2018 - Springer
Bacteriophages (phages) are viruses that infect bacteria. The “predator–prey” interactions
are recognized as a potentially effective way to treat infections. Phages, as well as phage …

Pharmacologically aware phage therapy: pharmacodynamic and pharmacokinetic obstacles to phage antibacterial action in animal and human bodies

K Dąbrowska, ST Abedon - Microbiology and Molecular Biology …, 2019 - Am Soc Microbiol
The use of viruses infecting bacteria (bacteriophages or phages) to treat bacterial infections
has been ongoing clinically for approximately 100 years. Despite that long history, the …

[HTML][HTML] Polymicrobial infections and biofilms: clinical significance and eradication strategies

VT Anju, S Busi, M Imchen, R Kumavath, MS Mohan… - Antibiotics, 2022 - mdpi.com
Biofilms are population of cells growing in a coordinated manner and exhibiting resistance
towards hostile environments. The infections associated with biofilms are difficult to control …

An overview of the public health challenges in diagnosing and controlling human foodborne pathogens

A Elbehiry, A Abalkhail, E Marzouk, AE Elmanssury… - Vaccines, 2023 - mdpi.com
Pathogens found in food are believed to be the leading cause of foodborne illnesses; and
they are considered a serious problem with global ramifications. During the last few …

Pseudomonas predators: understanding and exploiting phage–host interactions

J De Smet, H Hendrix, BG Blasdel… - Nature Reviews …, 2017 - nature.com
Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …

How phages overcome the challenges of drug resistant bacteria in clinical infections

M Taati Moghadam, N Amirmozafari… - Infection and Drug …, 2020 - Taylor & Francis
Nowadays the most important problem in the treatment of bacterial infections is the
appearance of MDR (multidrug-resistant), XDR (extensively drug-resistant) and PDR (pan …

Learning from bacteriophages-advantages and limitations of phage and phage-encoded protein applications

Z Drulis-Kawa, G Majkowska-Skrobek… - Current Protein and …, 2012 - ingentaconnect.com
The emergence of bacteria resistance to most of the currently available antibiotics has
become a critical therapeutic problem. The bacteria causing both hospital and community …