Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Induced pluripotent stem cells from farm animals

Y Su, J Zhu, S Salman, Y Tang - Journal of animal science, 2020 - academic.oup.com
The development of the induced pluripotent stem cells (iPSC s) technology has
revolutionized the world on the establishment of pluripotent stem cells (PSC s) across a …

Generation and characterization of stable pig pregastrulation epiblast stem cell lines

M Zhi, J Zhang, Q Tang, D Yu, S Gao, D Gao, P Liu… - Cell Research, 2022 - nature.com
Pig epiblast-derived pluripotent stem cells are considered to have great potential and broad
prospects for human therapeutic model development and livestock breeding. Despite …

Establishment of bovine trophoblast stem cells

Y Wang, H Ming, L Yu, J Li, L Zhu, HX Sun… - Cell Reports, 2023 - cell.com
Here, we report that a chemical cocktail (LCDM: leukemia inhibitory factor [LIF], CHIR99021,
dimethinedene maleate [DiM], minocycline hydrochloride), previously developed for …

Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing

JV Conrad, S Meyer, PS Ramesh, JA Neira… - Stem Cell Reports, 2023 - cell.com
Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical
studies because of its comparable physiology and organ size to humans. The derivation of …

Chemically defined and xeno-free culture condition for human extended pluripotent stem cells

B Liu, S Chen, Y Xu, Y Lyu, J Wang, Y Du, Y Sun… - Nature …, 2021 - nature.com
Extended pluripotent stem (EPS) cells have shown great applicative potentials in generating
synthetic embryos, directed differentiation and disease modeling. However, the lack of a …

The use of induced pluripotent stem cells in domestic animals: a narrative review

RA Scarfone, SM Pena, KA Russell, DH Betts… - BMC veterinary …, 2020 - Springer
Induced pluripotent stem cells (iPSCs) are undifferentiated stem cells characterized by the
ability to differentiate into any cell type in the body. iPSCs are a relatively new and rapidly …

[HTML][HTML] A critical review on induced totipotent stem cells: Types and methods

MH Ghazimoradi, A Khalafizadeh, S Babashah - Stem cell research, 2022 - Elsevier
Totipotent stem cells are cells with the capacity to form an entire embryo. Many attempts
have been made to convert other types of cells to totipotent stem cells which we called …

[HTML][HTML] Perspectives of pluripotent stem cells in livestock

D Kumar, TR Talluri, NL Selokar, I Hyder… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
The recent progress in derivation of pluripotent stem cells (PSCs) from farm animals opens
new approaches not only for reproduction, genetic engineering, treatment and conservation …

LCDM medium supports the derivation of bovine extended pluripotent stem cells with embryonic and extraembryonic potency in bovine–mouse chimeras from iPSCs …

J Xiang, H Wang, Y Zhang, J Wang, F Liu… - The FEBS …, 2021 - Wiley Online Library
Cattle have emerged as one of the most important domestic animals widely used for meat,
milk, and fur. Derivation of bovine pluripotent stem cells (PSCs) can be applied in drug …