Human platelet lysate: replacing fetal bovine serum as a gold standard for human cell propagation?

T Burnouf, D Strunk, MBC Koh, K Schallmoser - Biomaterials, 2016 - Elsevier
The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …

Platelet-rich plasma for managing pain and inflammation in osteoarthritis

I Andia, N Maffulli - Nature Reviews Rheumatology, 2013 - nature.com
Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing
response and progressive deterioration of the joint architecture. Autologous blood-derived …

Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors

PR Amable, RBV Carias, MVT Teixeira… - Stem cell research & …, 2013 - Springer
Introduction Platelet-rich plasma (PRP) is nowadays widely applied in different clinical
scenarios, such as orthopedics, ophthalmology and healing therapies, as a growth factor …

Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture …

M de Almeida Fuzeta, N Bernardes… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stromal cells (MSC) hold great promise for tissue engineering and cell-based
therapies due to their multilineage differentiation potential and intrinsic immunomodulatory …

Systematic review—the potential implications of different platelet-rich plasma (PRP) concentrations in regenerative medicine for tissue repair

P Gentile, S Garcovich - International journal of molecular sciences, 2020 - mdpi.com
The number of studies evaluating platelet-rich plasma (PRP) concentration has substantially
grown in the last fifteen years. A systematic review on this field has been realized by …

Blood-derived biomaterials and platelet growth factors in regenerative medicine

T Burnouf, HA Goubran, TM Chen, KL Ou, M El-Ekiaby… - Blood reviews, 2013 - Elsevier
Several biomaterials can be obtained from human blood. Some are used for clinical
indications requiring a high content in fibrinogen, while others are used because they …

Effect of autologous platelet-rich plasma treatment on refractory thin endometrium during the frozen embryo transfer cycle: a pilot study

H Kim, JE Shin, HS Koo, H Kwon, DH Choi… - Frontiers in …, 2019 - frontiersin.org
Objective: Thin or damaged endometrium remains to be an unsolved problem in the
treatment of patients with infertility. The empirical preference for endometrial thickness (EMT) …

Clinical efficacy of platelet-rich plasma injection and its association with growth factors in the treatment of mild to moderate knee osteoarthritis: a randomized double …

YB Park, JH Kim, CW Ha… - The American journal of …, 2021 - journals.sagepub.com
Background: Although platelet-rich plasma (PRP) has potential as a regenerative treatment
for knee osteoarthritis, its efficacy varies. Compositional differences among types of PRP …

The use of platelet-rich plasma in symptomatic knee osteoarthritis

TM Southworth, NB Naveen, TM Tauro… - The journal of knee …, 2019 - thieme-connect.com
With average life expectancy and the rising prevalence of obesity, osteoarthritis (OA) is
creating an increasingly large financial and physical burden on the US population today. As …

Leukocyte concentration and composition in platelet-rich plasma (PRP) influences the growth factor and protease concentrations

Y Kobayashi, Y Saita, H Nishio, H Ikeda… - Journal of Orthopaedic …, 2016 - Elsevier
Background Platelet-rich plasma (PRP) therapy has become an increasingly popular
treatment for orthopaedics and sports-related injuries, and various clinically available PRP …