Device and method for ultrasonic neuromodulation via stereotactic frame based technique

K Deisseroth, MB Schneider - US Patent 10,035,027, 2018 - Google Patents
One embodiment involves modifying neural transmission patterns between neural structures
and/or neural regions in a noninvasive manner. In a related exemplary method, sound …

Light-sensitive ion-passing molecules

K Deisseroth, F Zhang, V Gradinaru - US Patent 9,079,940, 2015 - Google Patents
2011-10-12 Assigned to THE BOARD OF TRUSTEES OF THE LELAND STANFORD
JUNIOR UNIVERSITY reassignment THE BOARD OF TRUSTEES OF THE LELAND …

Light-activated cation channel and uses thereof

K Deisseroth, ES Boyden - US Patent 8,906,360, 2014 - Google Patents
The present invention provides compositions and methods for light-activated cation channel
proteins and their uses within cell membranes and subcellular regions. The invention …

Light-activated cation channel and uses thereof

K Deisseroth, ES Boyden - US Patent 9,278,159, 2016 - Google Patents
The present invention provides compositions and methods for light-activated cation channel
proteins and their uses within cell membranes and subcellular regions. The invention …

System for optical stimulation of target cells

K Deisseroth, F Zhang, E Boyden - US Patent 8,398,692, 2013 - Google Patents
Various systems and methods are implemented for controlling stimulus of a cell. One such
method is implemented for optical stimulation of a cell expressing an NpHR ion pump. The …

Optical tissue interface method and apparatus for stimulating cells

K Deisseroth, A Aravanis, F Zhang… - US Patent …, 2016 - Google Patents
(63) Continuation-in-part of application No. 1 1/651,422, E. et 2. PNS EvC E49 ck filed on
Jan. 9, 2007, now Pat. No. 8,926.959, which is lomer et al., Journal OI Virology, f: s-- ss Fit t …

Systems, methods and compositions for optical stimulation of target cells

K Deisseroth, F Zhang, V Gradinaru - US Patent 8,603,790, 2013 - Google Patents
2.968, 302 A 1/1961 Fry et al. 3,131,690 A 5, 1964 Innis et al. includes engineering the light-
activated ion channel molecule 3,499.437 A 3, 1970 Balamuth et al. in a cell; and activating …

Optically-based stimulation of target cells and modifications thereto

K Deisseroth, O Yizhar, L Gunaydin… - US Patent …, 2014 - Google Patents
Stimulation of target cells using light, eg, in vivo or in vitro, is implemented using a variety of
methods and devices. One example involves a vector for delivering a light-activated …

Screening test drugs to identify their effects on cell membrane voltage-gated ion channel

K Deisseroth, F Zhang, V Gradinaru… - US Patent …, 2016 - Google Patents
5,741.316 A 4, 1998 Chen et al. 2003/0232339 A1 12/2003 Shu et al. 5.755. 750 A 5, 1998
Petruska et al. 2004/0023203 A1 2/2004 Miesenbocket al. 5,756.35. A 5, 1998 Isacoffetal …

Upconversion of light for use in optogenetic methods

K Deisseroth, P Anikeeva - US Patent 9,522,288, 2016 - Google Patents
(56) References Cited 2002/0193327 A1 12/2002 Nemerow et al. 2003, 0009103 A1 1/2003
Yuste et al. US PATENT DOCUMENTS 2003/0026784 A1 2/2003 Koch et al. 2003/0040080 …