Cytochrome c oxidase (COX) deficiency is characterized by a high degree of genetic and
phenotypic heterogeneity, partly reflecting the extreme structural complexity, multiple post …

Messenger RNA is a key component of an intricate regulatory network of its own. It
accommodates numerous nucleotide signals that overlap protein coding sequences and are …

The mitochondrion is arguably the most complex organelle in the budding yeast cell
cytoplasm. It is essential for viability as well as respiratory growth. Its innermost aqueous …

Eukaryotic cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial
respiratory chain. COX is a multimeric enzyme formed by subunits of dual genetic origin …

The Oxa1 translocase of the mitochondrial inner membrane facilitates the insertion of both
mitochondrially and nuclear‐encoded proteins from the matrix into the inner membrane …

Mitochondria contain their own genome which codes for a small number of proteins. Most
mitochondrial translation products are part of the membrane-embedded reaction centers of …

The post‐transcriptional role of Mss51p in mitochondrial gene expression is of great interest
since MSS51 mutations suppress the respiratory defect caused by shy1 mutations. SHY1 is …

The evolutionary origin of the photosynthetic eukaryotes drastically altered the evolution of
complex lifeforms and impacted global ecology. The endosymbiotic theory suggests that …

Together, the nuclear and mitochondrial genomes encode the oxidative phosphorylation
(OXPHOS) complexes that reside in the mitochondrial inner membrane and enable aerobic …

Biogenesis of the cytochrome oxidase complex in the mitochondrial inner membrane
depends on the concerted action of a variety of proteins. Recent studies shed light on this …