In recent years, the utilization of Chinese native medicine and other plant extracts in the
treatment of diseases has attracted extensive attention, especially in the area of malignant …

Purpose The objective of this review was to explore the potential clinical application of
unconventional non-amino acid PET radiopharmaceuticals in patients with gliomas …

Reporter gene imaging (RGI) can accelerate development timelines for gene and viral
therapies by facilitating rapid and noninvasive in vivo studies to determine the …

There is a growing need for monitoring or imaging gene therapy in the central nervous
system (CNS). This can be achieved with a positron emission tomography (PET) reporter …

Despite the anti-proliferative and survival benefits from tumor treating fields (TTFields) in
human glioblastoma (hGBM), little is known about the effects of this form of alternating …

The development of gene delivery vehicles with high organ specificity when administered
systemically is a critical goal for gene therapy. We combine optical and positron emission …

Abstract Purpose: Pyruvate kinase M2 (PKM2) catalyzes the final step in glycolysis, a key
process of cancer metabolism. PKM2 is preferentially expressed by glioblastoma (GBM) …

Purpose: To analyze and review the progress of glucose metabolism-based molecular
imaging in detecting tumors to guide clinicians for new management strategies. Summary …

Background Aerobic glycolysis is a hallmark of glucose metabolism in cancer. Previous
studies have suggested that cancer cell–derived extracellular vesicles (EVs) can modulate …

Purpose To assess the safety, biodistribution, and radiation dosimetry of the novel positron
emission tomography (PET) radiopharmaceutical 1-((2-fluoro-6-[[18 F]] fluorophenyl) …