Insights Into the Antiviral Pathways of the Silkworm Bombyx mori

L Jiang - Frontiers in immunology, 2021 - frontiersin.org
The lepidopteran model silkworm, Bombyx mori, is an important economic insect. Viruses
cause serious economic losses in sericulture; thus, the economic importance of these …

Structural insights into piRNA biogenesis

J Zhang, S Chen, K Liu - Biochimica et Biophysica Acta (BBA)-Gene …, 2022 - Elsevier
Discovered two decades ago, Piwi-interacting RNAs (piRNAs) play critical roles in gene
regulation, transposon element repression, and antiviral defense. Dysregulation of piRNAs …

A review of discovery profiling of PIWI-interacting RNAs and their diverse functions in metazoans

S Huang, K Yoshitake, S Asakawa - International Journal of Molecular …, 2021 - mdpi.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs (sncRNAs) that
perform crucial biological functions in metazoans and defend against transposable elements …

Reactivation of a somatic errantivirus and germline invasion in Drosophila ovaries

M Yoth, S Maupetit-Méhouas, A Akkouche… - Nature …, 2023 - nature.com
Most Drosophila transposable elements are LTR retrotransposons, some of which belong to
the genus Errantivirus and share structural and functional characteristics with vertebrate …

Current scenario of exogenously induced RNAi for Lepidopteran agricultural pest control: From dsRNA design to topical application

VS Lucena-Leandro, EFA Abreu, LA Vidal… - International Journal of …, 2022 - mdpi.com
Invasive insects cost the global economy around USD 70 billion per year. Moreover,
increasing agricultural insect pests raise concerns about global food security constraining …

Single-nucleus sequencing of silkworm larval midgut reveals the immune escape strategy of BmNPV in the midgut during the late stage of infection

J Xia, S Fei, Y Huang, W Lai, Y Yu, L Liang… - Insect Biochemistry and …, 2024 - Elsevier
The midgut is an important barrier against microorganism invasion and proliferation, yet is
the first tissue encountered when a baculovirus naturally invades the host. However, only …

Dissecting protein domain variability in the core RNA interference machinery of five insect orders

FBM Arraes, D Martins-de-Sa, DD Noriega Vasquez… - RNA biology, 2021 - Taylor & Francis
ABSTRACT RNA interference (RNAi)-mediated gene silencing can be used to control
specific insect pest populations. Unfortunately, the variable efficiency in the knockdown …

Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system

S Ikhlas, A Usman, D Kim, D Cai - Life Science Alliance, 2022 - life-science-alliance.org
Murine neural stem cells (NSCs) were recently shown to release piRNA-containing
exosomes/microvesicles (Ex/Mv) for exerting antiviral immunity, but it remains unknown if …

[HTML][HTML] Mussel antiviral transcriptome response and elimination of viral haemorrhagic septicaemia virus (VHSV)

A Saco, M Rey-Campos, B Novoa… - Fish & Shellfish …, 2023 - Elsevier
As filter-feeding bivalves, mussels have been traditionally studied as possible vectors of
different bacterial or viral pathogens. The absence of a known viral pathogen in these …

Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract

IA Amaro, YH Ahmed-Braimah, GP League, SA Pitcher… - BMC genomics, 2021 - Springer
Background Mating induces behavioral and physiological changes in the arbovirus vector
Aedes aegypti, including stimulation of egg development and oviposition, increased …