Subtype-specific cardiomyocytes for precision medicine: Where are we now?
Patient-derived pluripotent stem cells (PSCs) have greatly transformed the current
understanding of human heart development and cardiovascular disease. Cardiomyocytes …
understanding of human heart development and cardiovascular disease. Cardiomyocytes …
Multicellular In vitro Models of Cardiac Arrhythmias: Focus on Atrial Fibrillation
PRR Van Gorp, SA Trines, DA Pijnappels… - Frontiers in …, 2020 - frontiersin.org
Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice with a large
socioeconomic impact due to its associated morbidity, mortality, reduction in quality of life …
socioeconomic impact due to its associated morbidity, mortality, reduction in quality of life …
Effects of cryopreservation on human induced pluripotent stem cell-derived cardiomyocytes for assessing drug safety response profiles
Burgeoning applications of human induced pluripotent stem cell-derived cardiomyocytes
(hiPSC-CMs) in disease modeling, regenerative medicine, and drug screening have …
(hiPSC-CMs) in disease modeling, regenerative medicine, and drug screening have …
Towards systems tissue engineering: Elucidating the dynamics, spatial coordination, and individual cells driving emergent behaviors
Biomaterial systems have enabled the in vitro production of complex, emergent tissue
behaviors that were not possible with conventional two-dimensional culture systems …
behaviors that were not possible with conventional two-dimensional culture systems …
Fluorescent PSC-derived cardiomyocyte reporter lines: generation approaches and their applications in cardiovascular medicine
N Sontayananon, C Redwood, B Davies, K Gehmlich - Biology, 2020 - mdpi.com
Simple Summary Understanding how heart muscle cells function and developing new
strategies for repairing the damaged heart are important challenges for tackling heart …
strategies for repairing the damaged heart are important challenges for tackling heart …
Generation of functional human NKX2. 5GFP reporter cell lines for direct reprogramming into proliferative cardiac progenitors
L López-Muneta - 2021 - dadun.unav.edu
The mammalian heart is the first organ formed in the embryo and is composed of four
chambers: right atrium (RA), right ventricle (RV), left atrium (LA), and left ventricle (LV), and …
chambers: right atrium (RA), right ventricle (RV), left atrium (LA), and left ventricle (LV), and …
Reporter gene imaging “visualized” the integration of two growing technologies: CRISPR/Cas9-based genome editing and induced pluripotent stem cell therapy
A Chiti - European Journal of Nuclear Medicine and Molecular …, 2021 - Springer
Cardiovascular disease is the leading cause of morbidity and mortality worldwide. However,
the postmitotic human cardiomyocytes could not regenerate after injuries such as …
the postmitotic human cardiomyocytes could not regenerate after injuries such as …
[PDF][PDF] Fluorescent PSC-derived cardiomyocyte reporter lines
N Sontayananon, C Redwood, B Davies, K Gehmlich - research.birmingham.ac.uk
Recent advances have made pluripotent stem cell (PSC)-derived cardiomyocytes an
attractive option to model both normal and diseased cardiac function at the single-cell level …
attractive option to model both normal and diseased cardiac function at the single-cell level …
[引用][C] 1Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA 2Division of Cardiovascular Medicine, Department of Medicine …
JZ Zhang, N Belbachir, T Zhang, Y Liu, R Shrestha…