Endothelial cell metabolism

G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Diabetic microvascular disease: an endocrine society scientific statement

EJ Barrett, Z Liu, M Khamaisi, GL King… - The Journal of …, 2017 - academic.oup.com
Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

[PDF][PDF] Vascular complications of diabetes: mechanisms of injury and protective factors

C Rask-Madsen, GL King - Cell metabolism, 2013 - cell.com
In patients with diabetes, atherosclerosis is the main reason for impaired life expectancy,
and diabetic nephropathy and retinopathy are the largest contributors to end-stage renal …

Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing

GK Kolluru, SC Bir, CG Kevil - International journal of vascular …, 2012 - Wiley Online Library
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by inappropriate
hyperglycemia due to lack of or resistance to insulin. Patients with DM are frequently afflicted …

Angiogenesis and inflammation crosstalk in diabetic retinopathy

M Capitão, R Soares - Journal of cellular biochemistry, 2016 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most prevalent microvascular complications of
diabetes and one of the most frequent causes of blindness in active age. Etiopathogenesis …

Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use

GP Fadini, D Losordo, S Dimmeler - Circulation research, 2012 - Am Heart Assoc
Diverse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …

Acellular and cellular approaches to improve diabetic wound healing

H Cho, MR Blatchley, EJ Duh, S Gerecht - Advanced drug delivery reviews, 2019 - Elsevier
Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …

Endothelial progenitor cells: characterization and role in vascular biology

C Urbich, S Dimmeler - Circulation research, 2004 - Am Heart Assoc
Infusion of different hematopoietic stem cell populations and ex vivo expanded endothelial
progenitor cells augments neovascularization of tissue after ischemia and contributes to …

Human endothelial progenitor cells

MC Yoder - Cold Spring Harbor perspectives in …, 2012 - perspectivesinmedicine.cshlp.org
Human endothelial progenitor cells (EPCs) have been generally defined as circulating cells
that express a variety of cell surface markers similar to those expressed by vascular …

Advances in wound healing: a review of current wound healing products

PS Murphy, GRD Evans - Plastic surgery international, 2012 - Wiley Online Library
Successful wound care involves optimizing patient local and systemic conditions in
conjunction with an ideal wound healing environment. Many different products have been …