Colorectal cancer (CRC) is a malignancy in the gastro-intestinal (GI) tract which has very
limited treatment options still, despite the vast amount of research undertaken. CRC was first …

The difficulty of early diagnosis and the development of drug resistance are two major
barriers to the successful treatment of cancer. Autophagy plays a crucial role in several …

Background Glycolysis plays an essential role in the growth and metastasis of solid cancer
and has received increasing attention in recent years. However, the complex regulatory …

Lactobacillus plantarum (L. plantarum) is a probiotic that has emerged as novel therapeutic
agents for managing various diseases, such as cancer, atopic dermatitis, inflammatory …

Precision immunotherapy is a crucial approach to improve the efficacy of anti-cancer
treatments, particularly in the metastatic setting. In this respect, accurate patient selection …

Colorectal cancer is the third most prevalent malignancy in Western countries and a major
cause of death despite recent improvements in screening programs and early detection …

Colorectal cancer remains the third most common cancer worldwide and the second cause
of cancer-related death. Treatment advances and precision oncological medicine for these …

Colorectal cancer (CRC) is one of the most common gastrointestinal cancers worldwide with
high morbidity and mortality rates. The discovery of small molecule anticancer reagents has …

Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) recently emerged as a promising
cancer immunotherapy target. We set out to investigate the functional role of PTPN2 in the …

Proteomic analyses indicate that STAT1 protein (signal transducer and activator of
transcription 1 or transcription factor ISGF-3 components p91/p84) is upregulated in some …