Dopamine, erectile function and male sexual behavior from the past to the present: a review

MR Melis, F Sanna, A Argiolas - Brain Sciences, 2022 - mdpi.com
Early and recent studies show that dopamine through its neuronal systems and receptor
subtypes plays different roles in the control of male sexual behavior. These studies show …

Preclinical models of sexual desire: conceptual and behavioral analyses

A Ågmo, AL Turi, E Ellingsen, H Kaspersen - … Biochemistry and Behavior, 2004 - Elsevier
The epidemiology, etiology and proposed treatments for the sexual desire disorders are
briefly reviewed before turning to an analysis of preclinical models. We suggest that the …

Evaluating the neurobiology of sexual reward

RG Paredes - ILAR journal, 2009 - academic.oup.com
There is much evidence that naturally occurring behaviors (eg, the ingestion of food and
water) and social behaviors (eg, play, maternal behavior) can induce a reward state. This …

Sexual incentive motivation, olfactory preference, and activation of the vomeronasal projection pathway by sexually relevant cues in non-copulating and naive male …

W Portillo, RG Paredes - Hormones and behavior, 2004 - Elsevier
There are some apparently healthy male rats that fail to mate after repeated testing with
receptive females. We have previously shown that these “non-copulator (NC)” males show …

Opioids and sexual reward

RG Paredes - Pharmacology Biochemistry and Behavior, 2014 - Elsevier
Various lines of research indicate that sexual reward is mediated by opioids in both males
and females. In the first part I review basic ideas about sexual reward in humans followed by …

Modeling human sexual motivation in rodents: some caveats

O Le Moëne, A Ågmo - Frontiers in behavioral neuroscience, 2019 - frontiersin.org
Sexual behavior is activated by motivation. An overwhelming majority of experimental
studies of the intricacies of sexual motivation has been performed in rodents, most of them in …

Comparative analysis of immunoreactive cells for androgen receptors and oestrogen receptor α in copulating and non‐copulating male rats

W Portillo, NF Diaz, EA Cabrera… - Journal of …, 2006 - Wiley Online Library
In some species, including gerbils, guinea pigs, mice, rams and rats, some apparently
normal males fail to mate. These kinds of animals have been named 'noncopulating (NC)' …

Neurogenesis and sexual behavior

M Bedos, W Portillo, RG Paredes - Frontiers in Neuroendocrinology, 2018 - Elsevier
Different conditions induce proliferation, migration and integration of new neurons in the
adult brain. This process of neurogenesis is a clear example of long lasting plastic changes …

Background matters: the effects of estrogen receptor α gene disruption on male sexual behavior are modified by background strain

E Dominguez-Salazar, HL Bateman… - Hormones and Behavior, 2004 - Elsevier
One approach to study interactions between behavior and genetics is to use inbred mice
with different genetic backgrounds. To examine the effect of background on a specific gene …

Deficits in odor-guided behaviors in the transgenic 3xTg-AD female mouse model of Alzheimer׳ s disease

G Coronas-Sámano, W Portillo, VB Campos… - brain research, 2014 - Elsevier
Alzheimer׳ s disease (AD) is characterized by a number of alterations including those in
cognition and olfaction. An early symptom of AD is decreased olfactory ability, which may …