Antipsychotic treatment resistance affects up to a third of individuals with schizophrenia. Of
those affected, 70–84% are reported to be treatment resistant from the outset. This raises the …

Schizophrenia is a multifactorial disease associated with widespread cognitive impairment.
Although cognitive deficits are one of the factors most strongly associated with functional …

The paper by Green et al1 provides an extensive and in-depth review of cognition in
schizophrenia, supporting the argument that cognitive dysfunction is a core feature of the …

Clinical High Risk for Psychosis has evolved in recent years as a conceptual and clinical
entity, representing a shift in focus from the syndromal psychosis state to a recognition of the …

DISC1 was discovered as a gene disrupted by a balanced translocation in a large pedigree
that segregated with major mental disorders, including schizophrenia. Further attempts to …

Objective This study aimed to analyse whether intelligence quotient (IQ) improves, declines,
or remains stable over 10 years among FEP patients and healthy subjects. Methods A group …

Social anxiety disorder (SAD) is serious psychiatric condition with a genetic background.
Insight into the neurobiological alterations underlying the disorder is essential to develop …

Background: To study whether there is genetic overlap underlying the risk for schizophrenia
spectrum disorders (SSDs) and low intelligence quotient (IQ), we reviewed and summarized …

Purpose Patients with temporal lobe epilepsy (TLE) are at high risk of cognitive impairment.
In addition to persistent seizures and antiepileptic drugs (AEDs), genetic factors also play an …

BackgroundThe intelligence quotient (IQ) of patients with first-episode psychosis (FEP) and
their unaffected relatives may be related to the genetic burden of schizophrenia (SCZ). The …