[HTML][HTML] In Vitro and Ex Vivo Models of Microbial Keratitis: Present and Future
KKW Cheng, L Fingerhut, S Duncan, NV Prajna… - Progress in Retinal and …, 2024 - Elsevier
Microbial keratitis (MK) is an infection of the cornea, caused by bacteria, fungi, parasites, or
viruses. MK leads to significant morbidity, being the fifth leading cause of blindness …
viruses. MK leads to significant morbidity, being the fifth leading cause of blindness …
[HTML][HTML] Tolerability, pharmacokinetics, and anti-herpetic activity of orally administered BX795
Herpes simplex viruses type-1 (HSV-1) and type-2 (HSV-2) are ubiquitous human
pathogens causing serious pathologies in the ocular, orofacial and anogenital regions …
pathogens causing serious pathologies in the ocular, orofacial and anogenital regions …
[HTML][HTML] Heparanase 2 Modulation Inhibits HSV-2 Replication by Regulating Heparan Sulfate
J Hopkins, I Volety, F Qatanani, D Shukla - Viruses, 2024 - mdpi.com
The host enzyme heparanase (HPSE) facilitates the release of herpes simplex virus type 2
(HSV-2) from target cells by cleaving the viral attachment receptor heparan sulfate (HS) from …
(HSV-2) from target cells by cleaving the viral attachment receptor heparan sulfate (HS) from …