Characteristics and therapeutic potential of human amnion-derived stem cells

QW Liu, QM Huang, HY Wu, GSL Zuo, HC Gu… - International journal of …, 2021 - mdpi.com
Stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs)
and adult stem cells (ASCs) are able to repair/replace damaged or degenerative tissues and …

Application of human amniotic epithelial cells in regenerative medicine: a systematic review

Q Zhang, D Lai - Stem cell research & therapy, 2020 - Springer
Human amniotic epithelial cells (hAECs) derived from placental tissues have gained
considerable attention in the field of regenerative medicine. hAECs possess embryonic stem …

[HTML][HTML] Type 1 diabetes and engineering enhanced islet transplantation

A Jeyagaran, C Lu, A Zbinden, AL Birkenfeld… - Advanced drug delivery …, 2022 - Elsevier
The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D)
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …

Human amniotic epithelial stem cells: a promising seed cell for clinical applications

C Qiu, Z Ge, W Cui, L Yu, J Li - International journal of molecular sciences, 2020 - mdpi.com
Perinatal stem cells have been regarded as an attractive and available cell source for
medical research and clinical trials in recent years. Multiple stem cell types have been …

Current status and future prospects of perinatal stem cells

P Torre, AI Flores - Genes, 2020 - mdpi.com
The placenta is a temporary organ that is discarded after birth and is one of the most
promising sources of various cells and tissues for use in regenerative medicine and tissue …

Microvesicles and exosomes released by amnion epithelial cells under oxidative stress cause inflammatory changes in uterine cells

HI Shahin, E Radnaa, OAG Tantengco… - Biology of …, 2021 - academic.oup.com
Extracellular vesicles play a crucial role in feto-maternal communication and provide an
important paracrine signaling mechanism in pregnancy. We hypothesized that fetal cells …

Human placenta-derived amniotic epithelial cells as a new therapeutic hope for COVID-19-associated acute respiratory distress syndrome (ARDS) and systemic …

A Babajani, K Moeinabadi-Bidgoli, F Niknejad… - Stem Cell Research & …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus
disease 2019 (COVID-19), has become in the spotlight regarding the serious early and late …

The role of innate immune system in the human amniotic membrane and human amniotic fluid in protection against intra-amniotic infections and inflammation

T Šket, TŽ Ramuta, M Starčič Erjavec… - Frontiers in …, 2021 - frontiersin.org
Intra-amniotic infection and inflammation (IAI) affect fetal development and are highly
associated with preterm labor and premature rupture of membranes, which often lead to …

Therapeutic efficiency of human amniotic epithelial stem cell-derived functional hepatocyte-like cells in mice with acute hepatic failure

QW Liu, QY Liu, JY Li, L Wei, KK Ren… - Stem Cell Research & …, 2018 - Springer
Background Hepatocyte transplantation has been proposed as an effective treatment for
patients with acute liver failure (ALF), but its application is limited by a severe shortage of …

Naïve pluripotent-like characteristics of non-tumorigenic Muse cells isolated from human amniotic membrane

E Ogawa, Y Oguma, Y Kushida, S Wakao, K Okawa… - Scientific Reports, 2022 - nature.com
Multilineage-differentiating stress-enduring (Muse) cells are non-tumorigenic pluripotent-like
stem cells that exhibit triploblastic differentiation and self-renewability at the single-cell level …